WO2023223219 - IMPROVED PROTEIN PRODUCTION USING miRNA TECHNOLOGY
National phase entry:
Publication Number
WO/2023/223219
Publication Date
23.11.2023
International Application No.
PCT/IB2023/055054
International Filing Date
17.05.2023
Title **
[English]
IMPROVED PROTEIN PRODUCTION USING miRNA TECHNOLOGY
[French]
PRODUCTION AMÉLIORÉE DE PROTÉINES À L'AIDE DE LA TECHNOLOGIE DES MIARN
Applicants **
NOVARTIS AG
Inventors
AUSLAENDER, David
JOSTOCK, Thomas
Priority Data
63/343,876
19.05.2022
US
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
| Number of Priorities | * |
| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
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| Pages of Specification | * |
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| Number of Office Actions | * |
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International Searching Authority |
EPO
* |
| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
* |
| Type of Assignment |
The Standard Agent's Assignment
* |
| Applicant's Legal Status |
Legal Entity
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| * | |
| * | |
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| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| Translation |
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* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 2335 | |
| EPO | Filing, Examination, Granting | 10529 | |
| Japan | Filing, Examination, Granting | 2308 | |
| South Korea | Filing, Examination, Granting | 2335 | |
| USA | Filing, Examination, Granting | 5940 |
Total:
23,447
The term for entry into the National Phase has expired. This quotation is for informational purposes only
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Abstract[English]
The present invention pertains to the use of miRNA technology for improving recombinant production of polypeptides of interest in host cells. Expression cassettes are provided which produce a miRNA targeting and down-regulating a host cell protein which interferes with production of the polypeptide of interest.[French]
La présente invention concerne l'utilisation de la technologie des miARN pour améliorer la production recombinante de polypeptides d'intérêt dans des cellules hôtes. L'invention concerne également des cassettes d'expression qui produisent un miARN ciblant et régulant à la baisse une protéine de cellule hôte qui interfère avec la production du polypeptide d'intérêt.