WO2023104792 - ENHANCERS OF NEURONAL MATURATION

National phase entry is expected:
Publication Number WO/2023/104792
Publication Date 15.06.2023
International Application No. PCT/EP2022/084590
International Filing Date 06.12.2022
Title **
[English] ENHANCERS OF NEURONAL MATURATION
[French] AMPLIFICATEURS DE MATURATION NEURONALE
Applicants **
VIB VZW Suzanne Tassierstraat 1 9052 Gent, BE
KATHOLIEKE UNIVERSITEIT LEUVEN K.U.LEUVEN R&D Waaistraat 6 - bus 5105 3000 Leuven, BE
Inventors
VANDERHAEGHEN, Pierre 1180 Brussel, BE
CASIMIR, Pierre 1170 Brussel, BE
IWATA, Ryohei 1000 Brussel, BE
Priority Data
21212778.1   07.12.2021   EP
Application details
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Quotation for National Phase entry

Country StagesTotal
China Filing1339
EPO Filing, Examination5728
Japan Filing587
South Korea Filing574
USA Filing, Examination2710
MasterCard Visa

Total: 10938

The term for entry into the National Phase has expired. This quotation is for informational purposes only

Abstract[English] The present invention relates to the field of in vitro methods of inducing maturation of immature human pluripotent stem cell derived neurons into fully mature, electrically active neurons. The presently disclosed subject matter also provides for cells generated by such methods and uses of such cells for drug discovery purposes and/or treating neurodegenerative disorders.[French] La présente invention concerne le domaine des procédés in vitro d'induction de la maturation de neurones issus de cellules souches pluripotentes humaines immatures en neurones électriquement actifs entièrement matures. La présente invention concerne également des cellules générées par de tels procédés et des utilisations de ces cellules pour la découverte de médicaments et/ou le traitement de troubles neurodégénératifs.
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