WO2023104792 - ENHANCERS OF NEURONAL MATURATION

National phase entry is expected:
Publication Number WO/2023/104792
Publication Date 15.06.2023
International Application No. PCT/EP2022/084590
International Filing Date 06.12.2022
Title **
[English] ENHANCERS OF NEURONAL MATURATION
[French] AMPLIFICATEURS DE MATURATION NEURONALE
Applicants **
VIB VZW
KATHOLIEKE UNIVERSITEIT LEUVEN
Inventors
VANDERHAEGHEN, Pierre
CASIMIR, Pierre
IWATA, Ryohei
Priority Data
21212778.1   07.12.2021   EP
Application details
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译文

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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting2288
EPO Filing, Examination, Granting10349
Japan Filing, Examination, Granting2302
South Korea Filing, Examination, Granting2370
USA Filing, Examination, Granting4740
MasterCard Visa
Total: 22,049

The term for entry into the National Phase has expired. This quotation is for informational purposes only

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Abstract[English] The present invention relates to the field of in vitro methods of inducing maturation of immature human pluripotent stem cell derived neurons into fully mature, electrically active neurons. The presently disclosed subject matter also provides for cells generated by such methods and uses of such cells for drug discovery purposes and/or treating neurodegenerative disorders.[French] La présente invention concerne le domaine des procédés in vitro d'induction de la maturation de neurones issus de cellules souches pluripotentes humaines immatures en neurones électriquement actifs entièrement matures. La présente invention concerne également des cellules générées par de tels procédés et des utilisations de ces cellules pour la découverte de médicaments et/ou le traitement de troubles neurodégénératifs.