WO2025207537 - PREVENTION OF TOXICITY FROM HIGH CONCENTRATIONS OF CRYOPROTECTIVE AGENTS
National phase entry is expected:
Publication Number
WO/2025/207537
Publication Date
02.10.2025
International Application No.
PCT/US2025/021187
International Filing Date
24.03.2025
Title **
[English]
PREVENTION OF TOXICITY FROM HIGH CONCENTRATIONS OF CRYOPROTECTIVE AGENTS
[French]
PRÉVENTION DE LA TOXICITÉ ISSUE DE CONCENTRATIONS ÉLEVÉES D'AGENTS CRYOPROTECTEURS
Applicants **
21ST CENTURY MEDICINE, INC.
SHMOOKLER REIS, Robert J.
Inventors
MAZUR, Anna
FAHY, Gregory M.
Priority Data
63/569,191
24.03.2024
US
Application details
| Total Number of Claims/PCT | * |
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| Number of Drawings | * |
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International Searching Authority |
USPTO
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| * | |
| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
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| Type of Assignment |
The Standard Agent's Assignment
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| Applicant's Legal Status |
Legal Entity
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| * | |
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| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| Translation |
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* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 2338 | |
| EPO | Filing, Examination, Granting | 15663 | |
| Japan | Filing, Examination, Granting | 2430 | |
| South Korea | Filing, Examination, Granting | 2589 | |
| USA | Filing, Examination, Granting | 4910 |
Total:
27,930
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Abstract[English]
Cryoprotectant toxicity is a long-standing and limiting factor for the cryopreservation of many living systems. We now disclose methods by which this toxicity can be reduced or even eliminated by pre-exposing living cells, tissues, organs, and simple organisms to hydrogen peroxide or the equivalent and/or to non-toxic concentrations of cryoprotectants.[French]
La toxicité des cryoprotecteurs est un facteur limitant de longue date pour la cryoconservation de nombreux systèmes vivants. Des procédés par lesquels cette toxicité peut être réduite, voire éliminée, par pré-exposition de cellules vivantes, de tissus, d'organes et d'organismes simples au peroxyde d'hydrogène ou un équivalent et/ou à des concentrations non toxiques de cryoprotecteurs sont maintenant divulgués.