WO2025166073 - COMPOSITIONS COMPRISING ANTI-SORTILIN ANTIBODIES AND USES THEREOF
National phase entry is expected:
Publication Number
WO/2025/166073
Publication Date
07.08.2025
International Application No.
PCT/US2025/013884
International Filing Date
30.01.2025
Title **
[English]
COMPOSITIONS COMPRISING ANTI-SORTILIN ANTIBODIES AND USES THEREOF
[French]
COMPOSITIONS COMPRENANT DES ANTICORPS ANTI-SORTILINE ET LEURS UTILISATIONS
Applicants **
ALECTOR LLC
Inventors
BIENLY, Thunga
SHAN, Lu
BROWN, Eric
TONG, Raymond Ka-Hang
NIVITCHANYONG, Tarangsri
PINCETIC, Andrew
HO, Wei-Hsien
TANG, Margaret L.
YEE, Angie Grace
GULEVICH, Alexander Gregory
Priority Data
63/627,654
31.01.2024
US
63/660,922
17.06.2024
US
63/660,929
17.06.2024
US
63/744,149
10.01.2025
US
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
| Number of Priorities | * |
| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
| Pages for Publication | * |
| Number of Pages with Drawings | * |
| Pages of Specification | * |
| * | |
| Number of Office Actions | * |
| * | |
International Searching Authority |
USPTO
* |
| * | |
| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
* |
| Type of Assignment |
The Standard Agent's Assignment
* |
| Applicant's Legal Status |
Legal Entity
* |
| * | |
| * | |
| * | |
| * | |
| * | |
| Entry into National Phase under |
Chapter I
* |
| Patent Delivery |
Send the Letters Patent by Courier
* |
| Translation |
|
* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 9568 | |
| EPO | Filing, Examination, Granting | 111124 | |
| Japan | Filing, Examination, Granting | 4856 | |
| South Korea | Filing, Examination, Granting | 7756 | |
| USA | Filing, Examination, Granting | 42710 |
Total:
176,014
Contact Us
Abstract[English]
The present disclosure relates to multi-specific proteins comprising an antigen-binding domain linked to an anti-Sortilin antibody or antigen-binding fragment thereof. The antigen-binding domain can bind specifically to human transferrin receptor (TfR) or human CD98 heavy chain (CD98hc) to facilitate the transport of the anti-Sortilin antibody or antigen-binding fragment thereof across the blood brain barrier (BBB).[French]
La présente divulgation concerne des protéines multi-spécifiques comprenant un domaine de liaison à l'antigène lié à un anticorps anti-sortiline ou un fragment de liaison à l'antigène de celui-ci. Le domaine de liaison à l'antigène peut se lier de manière spécifique au récepteur de transferrine humaine (TfR) ou la chaîne lourde CD98 humaine (CD98hc) pour faciliter le transport de l'anticorps anti-sortiline ou le fragment de liaison à l'antigène de celui-ci à travers la barrière hémato-encéphalique (BBB).