WO2024220437 - COMPOSITIONS AND METHODS FOR DETERMINING THE EFFECTS OF T CELL ENGAGER
National phase entry is expected:
Publication Number
WO/2024/220437
Publication Date
24.10.2024
International Application No.
PCT/US2024/024813
International Filing Date
16.04.2024
Title **
[English]
COMPOSITIONS AND METHODS FOR DETERMINING THE EFFECTS OF T CELL ENGAGER
[French]
COMPOSITIONS ET PROCÉDÉS POUR DÉTERMINER LES EFFETS D'UN ACTIVATEUR DE LYMPHOCYTES T
Applicants **
ARBELE LIMITED
Unit 522, Biotech Center 2
11 Science Park West Ave.
Shatin
N.T., HK
Inventors
LUK, John Moonching
16425 SE 46th Ct.
Bellevue, Washington 98006, US
CHOW, Chu Qiao
25B, Block One, Scenery Court
Shatin, HK
LIN, Nga Ting
Flat 1, 5/F, Block B, Fortune Gardens, 11 Seymour Road
Hong Kong, HK
WONG, Dennis A.
Flat A, 6/F, 3 Tin Hau Temple Road, Hung on Building, North Point
Hong Kong, HK
Priority Data
63/459,937
17.04.2023
US
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
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| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
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| Number of Pages with Drawings | * |
| Pages of Specification | * |
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International Searching Authority |
USPTO
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| Applicant's Legal Status |
Legal Entity
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| * | |
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| Entry into National Phase under |
Chapter I
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| Translation |
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Recalculate
* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing | 1301 | |
| EPO | Filing, Examination | 8830 | |
| Japan | Filing | 530 | |
| South Korea | Filing | 575 | |
| USA | Filing, Examination | 2605 |
Total: 13841 USD
The term for entry into the National Phase has expired. This quotation is for informational purposes only
Abstract[English]
An assaying system to measure T cell engagement and disengagement to target cancer cells by T cell engager (TCE) antibodies, and its subsequent effects on T cells activation and proliferation. The assay platform may be used to screen TCE candidates that form detachable immune synapse and may provide long-term protection.[French]
L'invention concerne un système de dosage pour mesurer l'engagement et le désengagement des lymphocytes T pour cibler des cellules cancéreuses par des anticorps d'activateurs de lymphocytes T (TCE), et ses effets ultérieurs sur l'activation et la prolifération de lymphocytes T. La plateforme de dosage peut être utilisée pour cribler des TCE candidats qui forment une synapse immunitaire détachable et peuvent assurer une protection à long terme.