WO2024006353 - STERILE HUMAN PLACENTAL ALLOGRAFTS AND METHODS OF MAKING THEREOF

National phase entry is expected:
Publication Number WO/2024/006353
Publication Date 04.01.2024
International Application No. PCT/US2023/026447
International Filing Date 28.06.2023
Title **
[English] STERILE HUMAN PLACENTAL ALLOGRAFTS AND METHODS OF MAKING THEREOF
[French] ALLOGREFFES PLACENTAIRES HUMAINES STÉRILES ET LEURS PROCÉDÉS DE FABRICATION
Applicants **
BIOSTEM TECHNOLOGIES, INC. 2836 Center Port Circle Pompano Beach, FL 33064, US
Inventors
MATUSZEWSKI, Jason, V. 20985 Uptown Avenue Apt. 207 Boca Raton, FL 33428, US
WESTON, Wendy, W. 1946 NW 81st Avenue Coral Springs, FL 33071, US
Priority Data
63/356,628   29.06.2022   US
63/391,032   21.07.2022   US
63/395,426   05.08.2022   US
2033318   14.10.2022   NL
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Quotation for National Phase entry

Country StagesTotal
China Filing1922
EPO Filing, Examination11043
Japan Filing592
South Korea Filing673
USA Filing, Examination5835
MasterCard Visa

Total: 20065

The term for entry into the National Phase has expired. This quotation is for informational purposes only

Abstract[English] A method of preparing sterile human placental allografts by providing a human placental tissue from a donor within 24 hours to 72 hours post-childbirth; removing any visible blood, blood clots, and/or blood components from the human placental tissue without scraping or scrubbing the human placental tissue to preserve structural integrity of the human placental tissue; washing the human placental tissue in an isotonic solution while maintaining the structural integrity of the human placental tissue; dehydrating the human placental tissue thereby forming the dehydrated human placental tissue; resizing the dehydrated human placental tissue into dehydrated human placental tissue portions having predetermined sizes; and sterilizing the dehydrated human placental tissue portions of step (e) thereby forming the sterile human placental allograft. Also disclosed is a sterile human placental allograft produced by the method.[French] L'invention concerne un procédé de préparation d'allogreffes placentaires humaines stériles en fournissant un tissu placentaire humain à partir d'un donneur dans les 24 heures à 72 heures après l'accouchement; en éliminant le sang visible, les caillots sanguins visibles et/ou les composants sanguins visibles du tissu placentaire humain sans racler ou frotter le tissu placentaire humain pour préserver l'intégrité structurale du tissu placentaire humain; en lavant le tissu placentaire humain dans une solution isotonique tout en maintenant l'intégrité structurale du tissu placentaire humain; en déshydratant le tissu placentaire humain, formant ainsi le tissu placentaire humain déshydraté; en redimensionnant le tissu placentaire humain déshydraté en parties de tissu placentaire humain déshydraté ayant des tailles prédéterminées; et en stérilisant les parties de tissu placentaire humain déshydraté de l'étape (e), formant ainsi l'allogreffe placentaire humaine stérile. Est également divulguée une allogreffe placentaire humaine stérile produite par le procédé.
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