WO2026106497 - FUNCTIONALIZED CIRCULAR RNA AND METHODS AND INTERMEDIATES FOR THEIR PRODUCTION

National phase entry is expected:
Publication Number WO/2026/106497
Publication Date 21.05.2026
International Application No. PCT/PL2025/050088
International Filing Date 18.11.2025
Title **
[English] FUNCTIONALIZED CIRCULAR RNA AND METHODS AND INTERMEDIATES FOR THEIR PRODUCTION
[French] ARN CIRCULAIRE FONCTIONNALISÉ ET PROCÉDÉS ET INTERMÉDIAIRES POUR LEUR PRODUCTION
Applicants **
SIEĆ BADAWCZA ŁUKASIEWICZ – PORT POLSKI OSRODEK ROZWOJU TECHNOLOGII
Inventors
WARMIŃSKI, Marcin
KOWALSKA, Joanna
JEMIELITY, Jacek
WĄSIŃSKA-KAŁWA, Małgorzata
CZUBAK, Karol
GOŁĄB, Jakub
NOWIS, Dominika
FRANKOWSKA, Katarzyna
RZĄCA, Antoni
RAJKIEWICZ, Adam
Priority Data
24461634.8   18.11.2024   EP
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting3706
EPO Filing, Examination, Granting14596
Japan Filing, Examination, Granting2155
South Korea Filing, Examination, Granting2071
USA Filing, Examination, Granting7740
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Abstract[English] The present invention relates to circular RNA molecules, methods of producing circular RNA molecules, circular and non-circular intermediates thereof, and methods of treating or preventing a disease. In particular, the present invention provides circRNAs that can be prepared via chemical circularization of RNA, regardless of the circRNA sequence, length or size. Due to chemical nature of the circularization process, it allows the attachment of tags, markers, etc. after the circularization at a position in close proximity to the position where the circRNA was circularized.[French] La présente invention concerne des molécules d'ARN circulaire, des procédés de production de molécules d'ARN circulaire, leurs intermédiaires circulaires et non circulaires, et des méthodes de traitement ou de prévention d'une maladie. En particulier, la présente invention concerne des ARNc qui peuvent être préparés par circularisation chimique de l'ARN, indépendamment de la séquence, de la longueur ou de la taille de l'ARNc. En raison de la nature chimique du processus de circularisation, celui-ci permet la fixation d'étiquettes, de marqueurs, etc. après la circularisation, en une position à proximité immédiate de la position où l'ARNc a été circularisé.