WO2026099897 - NOVEL LINKERS AND ITS PREPARATION METHODS THEREOF
National phase entry is expected:
Publication Number
WO/2026/099897
Publication Date
15.05.2026
International Application No.
PCT/IN2025/051760
International Filing Date
10.11.2025
Title **
[English]
NOVEL LINKERS AND ITS PREPARATION METHODS THEREOF
[French]
NOUVEAUX LIEURS ET LEURS PROCÉDÉS DE FABRICATION
Applicants **
ZYDUS LIFESCIENCES LIMITED
Inventors
IYER, Pravin
NAGASWAMY, Kumargurubaran
BAHEKAR, Rajesh
CHOPADE, Rajendra
SINGH, Avanish Kumar
KALITA, Pankaj
MENDIRATTA, Sanjeev Kumar
BANDYOPADHYAY, Sanjay
Priority Data
202421086335
09.11.2024
IN
Application details
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International Searching Authority |
IP India
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| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
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| Type of Assignment |
The Standard Agent's Assignment
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| Applicant's Legal Status |
Legal Entity
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| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| Translation |
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Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 2143 | |
| EPO | Filing, Examination, Granting | 12036 | |
| Japan | Filing, Examination, Granting | 2061 | |
| South Korea | Filing, Examination, Granting | 1937 | |
| USA | Filing, Examination, Granting | 7740 |
Total:
25,917
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Abstract[English]
The present invention relates to a novel linker for Antibody-drug conjugates (ADCs), Peptide- drug conjugates (PDCs) and a preparation method for it, wherein the linker's one end can selectively and covalently link a targeting substance, and its other end can covalently link to a small molecule compound or a cytotoxic payload. The linkers of the present invention can be used to prepare an antibody drug conjugate, and it can be used for various applications including anticancer activity and other medicinal uses.[French]
La présente invention concerne un nouveau lieur pour conjugués anticorps-médicament (ADC), des conjugués peptide-médicament (PDC) et un procédé de préparation associée, l'extrémité du lieur pouvant lier sélectivement et de manière covalente une substance de ciblage, et son autre extrémité pouvant se lier de manière covalente à un composé à petite molécule ou à une charge utile cytotoxique. Les lieurs selon la présente invention peuvent être utilisés pour préparer un conjugué anticorps-médicament, et peuvent être utilisés pour diverses applications comprenant une activité anticancéreuse et d'autres utilisations médicales.