WO2026133214 - FAP TARGETING COMPOUNDS AND CONJUGATES THEREOF

National phase entry is expected:
Publication Number WO/2026/133214
Publication Date 25.06.2026
International Application No. PCT/IB2025/063093
International Filing Date 17.12.2025
Title **
[English] FAP TARGETING COMPOUNDS AND CONJUGATES THEREOF
[French] COMPOSÉS CIBLANT LA FAP ET CONJUGUÉS DE CEUX-CI
Applicants **
NOVARTIS AG
Inventors
ACKER, Vincent Jean François
BAUMANN, Anja
BERST, Frédéric
CLEMENTE, Gonçalo dos Santos
DUMELIN, Christoph
FISCHER, Matteo
GOLOSOV, Andrei Alexandrovich
HOLZER, Philipp
KIEFFER, Laurence
MAURO, Emanuele
MEIER, Peter
PARK, Danielle Rose
RESCHKE, Markus Oliver
SELLNER, Holger
STACHYRA, Thérèse-Marie
Priority Data
63/736,785   20.12.2024   US
63/837,446   02.07.2025   US
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting8208
EPO Filing, Examination, Granting123697
Japan Filing, Examination, Granting5014
South Korea Filing, Examination, Granting9191
USA Filing, Examination, Granting30840
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Total: 176,950
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Abstract[English] Described herein are compounds targeting fibroblast activation protein (FAP), and their incorporation into compounds for radioligand imaging and therapies, as well as methods and/or uses of such compounds for the imaging, treatment and/or prevention of FAP- implicated diseases and disorders.[French] Sont décrits ici des composés ciblant la protéine d'activation des fibroblastes (FAP), ainsi que leur incorporation dans des composés destinés à l'imagerie par radioligands et aux thérapies associées, de même que des méthodes et/ou des utilisations de ces composés pour l'imagerie, le traitement et/ou la prévention de maladies et de troubles impliquant la FAP.