WO2026120530 - NLRP3 INHIBITOR FOR USE IN TREATING MYELOID DISEASES

National phase entry is expected:
Publication Number WO/2026/120530
Publication Date 11.06.2026
International Application No. PCT/IB2025/062426
International Filing Date 04.12.2025
Title **
[English] NLRP3 INHIBITOR FOR USE IN TREATING MYELOID DISEASES
[French] INHIBITEUR DE NLRP3 DESTINÉ À ÊTRE UTILISÉ DANS LE TRAITEMENT DE MALADIES MYÉLOÏDES
Applicants **
NOVARTIS AG
Inventors
BEAULIEU, Valerie
CARREON, Daniel
GATLIK, Ewa
GONZALEZ-MAFFE, Juan
LI, Yutong
RAUCH, Philipp
SINGH, Arti
WOO, Janghee
Priority Data
63/728,851   06.12.2024   US
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting3031
EPO Filing, Examination, Granting17617
Japan Filing, Examination, Granting2587
South Korea Filing, Examination, Granting2951
USA Filing, Examination, Granting6990
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Total: 33,176
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Abstract[English] The present disclosure relates to the field of pharmacy, particularly to a NLRP3 inhibitor, for use in treating myeloid diseases, in particular myelodysplastic syndrome (MDS), chronic myelomonocytic leukemia (CMML), clonal hematopoiesis of indeterminate potential (CHIP) and clonal cytopenia of undetermined significance (CCUS), for the manufacture of a medicament for treating myeloid diseases, in particular myelodysplastic syndrome (MDS), chronic myelomonocytic leukemia (CMML), clonal hematopoiesis of indeterminate potential (CHIP) and clonal cytopenia of undetermined significance (CCUS).[French] La présente divulgation concerne le domaine de la pharmacie, en particulier un inhibiteur de NLRP3, destiné à être utilisé dans le traitement de maladies myéloïdes, notamment le syndrome myélodysplasique (SMD), la leucémie myélomonocytaire chronique (LMMC), l'hématopoïèse clonale de potentiel indéterminé (CHIP) et la cytopénie clonale de signification indéterminée (CCUS), pour la fabrication d'un médicament destiné au traitement de maladies myéloïdes, notamment le syndrome myélodysplasique (SMD), la leucémie myélomonocytaire chronique (LMMC), l'hématopoïèse clonale de potentiel indéterminé (CHIP) et la cytopénie clonale de signification indéterminée (CCUS).