WO2026083296 - TRISPECIFIC COMPOSITIONS COMPRISING IL-18, VEGF BINDING DOMAINS, AND PD-1 BINDING DOMAINS
National phase entry is expected:
Publication Number
WO/2026/083296
Publication Date
23.04.2026
International Application No.
PCT/IB2025/060509
International Filing Date
15.10.2025
Title **
[English]
TRISPECIFIC COMPOSITIONS COMPRISING IL-18, VEGF BINDING DOMAINS, AND PD-1 BINDING DOMAINS
[French]
COMPOSITIONS TRISPÉCIFIQUES COMPRENANT IL-18, DOMAINES DE LIAISON AU VEGF ET DOMAINES DE LIAISON À PD-1
Applicants **
BRIGHT PEAK THERAPEUTICS AG
Inventors
PATTABIRAMAN, Vijaya Raghavan
KREFT, Bertolt
GOEPFERT, Arnaud
MARTIN, Kea
BORNERT, Olivier
RESCHKE, Nina
Priority Data
63/708,087
16.10.2024
US
63/739,331
27.12.2024
US
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
| Number of Priorities | * |
| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
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| Number of Pages with Drawings | * |
| Pages of Specification | * |
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| Number of Office Actions | * |
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International Searching Authority |
EPO
* |
| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
* |
| Type of Assignment |
The Standard Agent's Assignment
* |
| Applicant's Legal Status |
Legal Entity
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| * | |
| * | |
| * | |
| * | |
| * | |
| Entry into National Phase under |
Chapter I
* |
| Patent Delivery |
Send the Letters Patent by Courier
* |
| Translation |
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* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 8154 | |
| EPO | Filing, Examination, Granting | 179910 | |
| Japan | Filing, Examination, Granting | 5266 | |
| South Korea | Filing, Examination, Granting | 12135 | |
| USA | Filing, Examination, Granting | 36390 |
Total:
241,855
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Abstract[English]
The present disclosure relates anti-PD-1/anti-VEGF immunocytokines, particularly with IL-18. Also described herein are new formats of bispecific anti-PD-1 and anti-VEGF constructs. Further described herein are IL-18 / anti-VEGF immunocytokines. Also provided herein are pharmaceutical composition and methods of treatment using the same.[French]
La présente divulgation concerne des immunocytokines anti-PD-1/anti-VEGF, en particulier avec IL-18. L'invention concerne également de nouveaux formats de constructions anti-PD-1 et anti-VEGF bispécifiques. L'invention concerne en outre des immunocytokines IL-18/anti-VEGF. L'invention concerne également une composition pharmaceutique et des méthodes de traitement les utilisant.