WO2026038193 - NATURAL KILLER (NK) CELLS CRYOPRESERVATION

National phase entry is expected:
Publication Number WO/2026/038193
Publication Date 19.02.2026
International Application No. PCT/IB2025/058297
International Filing Date 15.08.2025
Title **
[English] NATURAL KILLER (NK) CELLS CRYOPRESERVATION
[French] CRYOCONSERVATION DE CELLULES TUEUSES NATURELLES (NK)
Applicants **
TAKEDA PHARMACEUTICAL COMPANY LIMITED
Inventors
JONES, Peter Anthony
ANDREEV, Nadejda
Priority Data
63/683,525   15.08.2024   US
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting3763
EPO Filing, Examination, Granting43852
Japan Filing, Examination, Granting3636
South Korea Filing, Examination, Granting5089
USA Filing, Examination, Granting16940
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Total: 73,280
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Abstract[English] The present invention provides, among other things, compositions and methods for protecting cell therapy products from cryoinjury, in particular immune cells (e.g., NK cell products), during cryopreservation. The cryoformulation compositions and methods of the present invention reduce cryoinjury during cryopreserving process, thereby increasing cell therapy product recovery, viability and function after cryopreservation.[French] La présente invention concerne, entre autres, des compositions et des procédés pour protéger des produits de thérapie cellulaire contre une cryolésion, en particulier des cellules immunitaires (par exemple, des produits de cellules NK), pendant la cryoconservation. Les compositions de cryoformulation et les procédés de la présente invention réduisent la cryolésion pendant le processus de cryoconservation, ce qui permet d'augmenter la récupération, la viabilité et la fonction du produit de thérapie cellulaire après cryoconservation.