WO2026028181 - METHODS OF TREATING PLANTAR FIBROMATOSIS

National phase entry is expected:
Publication Number WO/2026/028181
Publication Date 05.02.2026
International Application No. PCT/IB2025/057874
International Filing Date 01.08.2025
Title **
[English] METHODS OF TREATING PLANTAR FIBROMATOSIS
[French] MÉTHODES DE TRAITEMENT DE LA FIBROMATOSE PLANTAIRE
Applicants **
ENDO BIOLOGICS LIMITED
Inventors
TURSI, James P.
XIANG, Qinfang
ORTEGA, Luis A.
VIJAYAN, Saji
LEHRMAN, Jeffrey David
HERNANDEZ, David
Priority Data
63/678,664   02.08.2024   US
63/764,721   28.02.2025   US
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting4969
EPO Filing, Examination, Granting30785
Japan Filing, Examination, Granting2803
South Korea Filing, Examination, Granting3566
USA Filing, Examination, Granting12160
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Total: 54,283
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Abstract[English] Disclosed herein are methods of treating plantar fibromatosis in a subject or a population of subjects. Where the methods of treatment include intralesionally injecting a pharmaceutical formulation comprising collagenase into one or more plantar fibromatosis nodules in one or both of the subject's feet or the population of subjects' feet to thereby treat the plantar fibromatosis. The collagenase has enzymatic activity in regards to collagen. The treatment may result in a change from a baseline or control of a scale to determine effectiveness.[French] L'invention concerne des méthodes de traitement de la fibromatose plantaire chez un sujet ou une population de sujets. Les méthodes de traitement comprennent l'injection intralésionnelle d'une formulation pharmaceutique comprenant de la collagénase dans un ou plusieurs nodules de fibromatose plantaire au niveau des pieds du sujet et/ou de la population de pieds de sujets pour ainsi traiter la fibromatose plantaire. La collagénase a une activité enzymatique vis-à-vis du collagène. Le traitement peut conduire à un changement d'une base de référence ou d'un témoin d'une échelle pour déterminer l'efficacité.