WO2026028168 - DETECTION OF NUCLEIC ACID SEQUENCES
National phase entry is expected:
Publication Number
WO/2026/028168
Publication Date
05.02.2026
International Application No.
PCT/IB2025/057843
International Filing Date
01.08.2025
Title **
[English]
DETECTION OF NUCLEIC ACID SEQUENCES
[French]
DÉTECTION DE SÉQUENCES D'ACIDES NUCLÉIQUES
Applicants **
NEW YORK UNIVERSITY IN ABU DHABI CORPORATION
Inventors
SHUBEITA, George
DAS, Anand Kant
Priority Data
63/678,502
01.08.2024
US
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
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| Number of Multi-Dependent Claims | * |
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| Pages of Specification | * |
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International Searching Authority |
MOIP
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| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
* |
| Type of Assignment |
The Standard Agent's Assignment
* |
| Applicant's Legal Status |
Legal Entity
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| * | |
| * | |
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| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| Translation |
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* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 2648 | |
| EPO | Filing, Examination, Granting | 20397 | |
| Japan | Filing, Examination, Granting | 2678 | |
| South Korea | Filing, Examination, Granting | 2372 | |
| USA | Filing, Examination, Granting | 7140 |
Total:
35,235
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Abstract[English]
The present disclosure provides an enzyme-free, amplification-free optical method to detect ultra-low concentrations of microbial nucleic acids. The technique relies on detecting high signal-to-noise signals (e.g., fluorescent readouts of hybridization) between target nucleic acid sequences and complementary probes immobilized on the surface of a detection cell. The technique simplifies and accelerates diagnosis workflow, significantly reduces costs, and outperforms existing methods that rely heavily on the use of enzymes, are often time-consuming, and require specialized equipment and trained personnel.[French]
La présente invention concerne un procédé optique sans enzyme et sans amplification permettant de détecter des concentrations ultra-faibles d'acides nucléiques microbiens. La technique repose sur la détection de signaux à haut rapport signal/bruit (par exemple, des signaux fluorescents d'hybridation) entre des séquences d'acides nucléiques cibles et des sondes complémentaires immobilisées à la surface d'une cellule de détection. Cette technique simplifie et accélère le processus de diagnostic, réduit considérablement les coûts et surpasse les procédés existants fortement dépendants de l'utilisation d'enzymes, souvent longs à mettre en œuvre et nécessitant un équipement spécialisé et un personnel qualifié.