WO2026018221 - CRYSTALLINE COMPOSITIONS FOR IMPROVING EMBRYO IMPLANTATION AND METHODS OF USING THE SAME
National phase entry is expected:
Publication Number
WO/2026/018221
Publication Date
22.01.2026
International Application No.
PCT/IB2025/057317
International Filing Date
18.07.2025
Title **
[English]
CRYSTALLINE COMPOSITIONS FOR IMPROVING EMBRYO IMPLANTATION AND METHODS OF USING THE SAME
[French]
COMPOSITIONS CRISTALLINES POUR AMÉLIORER L'IMPLANTATION D'EMBRYONS ET LEURS PROCÉDÉS D'UTILISATION
Applicants **
REPRONOVO SA
Inventors
GOTTELAND, Jean-Pierre
Priority Data
63/673,132
18.07.2024
US
Application details
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International Searching Authority |
EPO
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| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
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| Type of Assignment |
The Standard Agent's Assignment
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| Applicant's Legal Status |
Legal Entity
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| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| Translation |
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* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 4246 | |
| EPO | Filing, Examination, Granting | 45666 | |
| Japan | Filing, Examination, Granting | 3634 | |
| South Korea | Filing, Examination, Granting | 5072 | |
| USA | Filing, Examination, Granting | 20390 |
Total:
79,008
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Abstract[English]
The disclosure provides crystalline forms of (3Z,5S)-5-(hydroxymethyl)-1-[(2'-methyl-1,1'-biphenyl-4-5 yl)carbonyl]pyrrolidin-3-one O-methyloxime, as well as methods of using this crystalline material to improve embryo implantation outcomes in patients undergoing an assisted reproduction technology (ART) procedure, such as in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI).[French]
L'invention concerne des formes cristallines de (3Z,5S)-5-(hydroxyméthyl)-1-[(2'-méthyl-1,1'-biphényl-4-5 yl)carbonyl]pyrrolidin-3-one O-méthyloxime, ainsi que des procédés d'utilisation de ce matériau cristallin pour améliorer les résultats d'implantation d'embryons chez des patients subissant une opération de technologie de reproduction assistée (ART), telle qu'une fécondation in vitro (FIV) ou une injection de sperme intracytoplasmique (ICSI).