WO2025215536 - MACROCYCLIC PANRAS INHIBITORS FOR THE TREATMENT OF CANCER
National phase entry is expected:
Publication Number
WO/2025/215536
Publication Date
16.10.2025
International Application No.
PCT/IB2025/053708
International Filing Date
08.04.2025
Title **
[English]
MACROCYCLIC PANRAS INHIBITORS FOR THE TREATMENT OF CANCER
[French]
INHIBITEURS DE PANRAS MACROCYCLIQUES POUR LE TRAITEMENT DU CANCER
Applicants **
NOVARTIS AG
Inventors
CHEN, Zhuoliang
CHIANG, Yingling
CONNORS, William Francis
FUREGATI, Markus Reto
GAO, Xin
GULLEDGE, Zachary Zephenia
HINDS, Aaron Bret
KAWANAMI, Toshio
LAFRANCE, Marc
MCNEILL, Eric Andrew
MOEBITZ, Henrik
NAKAJIMA, Katsumasa
SCHWALEN, Christopher Joseph
SHEN, Yiping
THOMAS, Ranny Mathew
WZOREK JR, Joseph S.
ZECRI, Frédéric Jean
ZHANG, Qiang
Priority Data
63/632,181
10.04.2024
US
63/698,688
25.09.2024
US
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
| Number of Priorities | * |
| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
| Pages for Publication | * |
| Number of Pages with Drawings | * |
| Pages of Specification | * |
| * | |
| Number of Office Actions | * |
| * | |
International Searching Authority |
EPO
* |
| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
* |
| Type of Assignment |
The Standard Agent's Assignment
* |
| Applicant's Legal Status |
Legal Entity
* |
| * | |
| * | |
| * | |
| * | |
| * | |
| Entry into National Phase under |
Chapter I
* |
| Patent Delivery |
Send the Letters Patent by Courier
* |
| Translation |
|
* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 6040 | |
| EPO | Filing, Examination, Granting | 63626 | |
| Japan | Filing, Examination, Granting | 3941 | |
| South Korea | Filing, Examination, Granting | 5749 | |
| USA | Filing, Examination, Granting | 46990 |
Total:
126,346
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Abstract[English]
The present invention relates to compounds of the formulae (I) or (XX) that are panRAS inhibitors for use in a method of treating cancer.[French]
La présente invention concerne des composés de formules (I) ou (XX) qui sont des inhibiteurs de panRAS destinés à être utilisés dans une méthode de traitement du cancer.