WO2025215516 - GLYCOENGINEERED POLYPEPTIDES TARGETING IGG4 AUTOANTIBODIES AND USES THEREOF
National phase entry is expected:
Publication Number
WO/2025/215516
Publication Date
16.10.2025
International Application No.
PCT/IB2025/053675
International Filing Date
08.04.2025
Title **
[English]
GLYCOENGINEERED POLYPEPTIDES TARGETING IGG4 AUTOANTIBODIES AND USES THEREOF
[French]
POLYPEPTIDES GLYCOMODIFIÉS CIBLANT DES AUTO-ANTICORPS ANTI-IGG4 ET LEURS UTILISATIONS
Applicants **
GLYCOERA AG
Inventors
KAUNDINYA, Ganesh Venkataraman
GANGULY, Tanmoy Chinmoy
HANES, Melinda Sue
MANNI, Michela
BACK, Jonathan Albert
REED, Brendan
MALLY, Manuela
COTTER, Kellie
SCHELBERT, Tina
FOLLADOR, Rainer
SIRENA, Dominique Nicolas
BEHRENS, Anna-Janina
FARIDMOAYER, Amirreza
Priority Data
63/631,250
08.04.2024
US
Application details
| Total Number of Claims/PCT | * |
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International Searching Authority |
EPO
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| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
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| Type of Assignment |
The Standard Agent's Assignment
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| Applicant's Legal Status |
Legal Entity
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| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| Translation |
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* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 6392 | |
| EPO | Filing, Examination, Granting | 49883 | |
| Japan | Filing, Examination, Granting | 3639 | |
| South Korea | Filing, Examination, Granting | 4782 | |
| USA | Filing, Examination, Granting | 20840 |
Total:
85,536
Abstract[English]
Provided herein are glycoengineered polypeptides comprising a first moiety comprising one or more peptides that specifically binds to an IgG4 antibody (e.g., an IgG4 autoantibody) and a second moiety comprising one or more glycans conjugated to the first moiety at one or more glycosylation sites. Further provided herein are compositions comprising glycoengineered polypeptides and/or nucleic acids encoding the same, as well as methods of making and using the same.[French]
La présente invention concerne des polypeptides glycomodifiés comprenant une première fraction comprenant un ou plusieurs peptides qui se lient de manière spécifique à un anticorps anti-IgG4 (par exemple un auto-anticorps anti-IgG4) et une seconde fraction comprenant un ou plusieurs glycanes conjugués à la première fraction au niveau d'un ou de plusieurs sites de glycosylation. L'invention concerne en outre des compositions comprenant des polypeptides glycomodifiés et/ou des acides nucléiques codant pour ceux-ci, ainsi que leurs procédés de fabrication et d'utilisation.