WO2025181649 - SYSTEMS AND METHODS FOR RAPID LIQUID BIOPRINTING
National phase entry is expected:
Publication Number
WO/2025/181649
Publication Date
04.09.2025
International Application No.
PCT/IB2025/051949
International Filing Date
24.02.2025
Title **
[English]
SYSTEMS AND METHODS FOR RAPID LIQUID BIOPRINTING
[French]
SYSTÈMES ET PROCÉDÉS DE BIO-IMPRESSION LIQUIDE RAPIDE
Applicants **
INNOCENT MEAT GMBH
Inventors
DRESCHER, Philipp
Priority Data
63/557,613
26.02.2024
US
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
| Number of Priorities | * |
| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
| Pages for Publication | * |
| Number of Pages with Drawings | * |
| Pages of Specification | * |
| * | |
| Number of Office Actions | * |
| * | |
International Searching Authority |
EPO
* |
| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
* |
| Type of Assignment |
The Standard Agent's Assignment
* |
| Applicant's Legal Status |
Legal Entity
* |
| * | |
| * | |
| * | |
| * | |
| * | |
| Entry into National Phase under |
Chapter I
* |
| Patent Delivery |
Send the Letters Patent by Courier
* |
| Translation |
|
* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 2316 | |
| EPO | Filing, Examination, Granting | 13206 | |
| Japan | Filing, Examination, Granting | 2462 | |
| South Korea | Filing, Examination, Granting | 2693 | |
| USA | Filing, Examination, Granting | 5740 |
Total:
26,417
Contact Us
Abstract[English]
Methods for fabricating three-dimensional (3D) constructs from a mixture of cells, culture medium, and a scaffold material with a controlled calcium chloride concentration is disclosed. The process involves positioning a nozzle within a gel composed of alginate solution. The nozzle is then moved within the gel, releasing the cell-media-scaffold mixture in a controlled pattern. As the mixture is deposited, it becomes surrounded by the gel, which provides structural support until it solidifies through the cross-linking reaction between the calcium chloride in the cell-media-scaffold mixture and the alginate solution. This results in the formation of a solid 3D structure that incorporates the cells and their supporting scaffold. The presented method offers a versatile platform for generating intricate cell-based 3D constructs with precise control over their composition and structure. This method can be used to produce cultivated meat with complex 3D structures as well as organelles and fully functional organs.[French]
La présente invention concerne des procédés de fabrication de constructions tridimensionnelles (3D) à partir d'un mélange de cellules, d'un milieu de culture et d'une matière d'échafaudage dont la concentration en chlorure de calcium est régulée. Le procédé consiste à positionner une buse à l'intérieur d'un gel composé d'une solution d'alginate. La buse est ensuite déplacée à l'intérieur du gel, libérant le mélange cellule-milieu-échafaudage selon un schéma régulé. Au fur et à mesure que le mélange est déposé, il est entouré par le gel, qui fournit un support structurel jusqu'à ce qu'il se solidifie par la réaction de réticulation entre le chlorure de calcium dans le mélange cellule-milieu-échafaudage et la solution d'alginate. Il en résulte la formation d'une structure 3D solide qui incorpore les cellules et leur échafaudage de soutien. Le procédé selon la présente invention offre une plateforme polyvalente pour générer des constructions 3D complexes à base de cellules, avec une maîtrise précise de la composition et de la structure de ces dernières. Ce procédé peut être utilisé pour produire de la viande cultivée à structure 3D complexe ainsi que des organites et des organes entièrement fonctionnels.