WO2025177174 - SINGLE-CELL RNA PROFILING
National phase entry is expected:
Publication Number
WO/2025/177174
Publication Date
28.08.2025
International Application No.
PCT/IB2025/051788
International Filing Date
19.02.2025
Title **
[English]
SINGLE-CELL RNA PROFILING
[French]
PROFILAGE D'ARN UNICELLULAIRE
Applicants **
DIAGENODE S.A.
Inventors
BROCART, Gilles Robert Charles
PALACIO, Ana Fernández
SABATEL, Céline Michelle Jacqueline
Priority Data
63/555,796
20.02.2024
US
Application details
| Total Number of Claims/PCT | * |
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| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
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International Searching Authority |
EPO
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| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
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| Type of Assignment |
The Standard Agent's Assignment
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| Applicant's Legal Status |
Legal Entity
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| * | |
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| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| Translation |
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* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 2677 | |
| EPO | Filing, Examination, Granting | 17051 | |
| Japan | Filing, Examination, Granting | 2649 | |
| South Korea | Filing, Examination, Granting | 3077 | |
| USA | Filing, Examination, Granting | 6940 |
Total:
32,394
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Abstract[English]
The invention provides methods for sequencing RNA molecules from single cells. Initial steps are performed on separate populations of RNA from individual cells, but sequencing and sometimes other steps, such as amplification, are performed after pooling of the populations from individual cells. Sequences can be deconvoluted to their original cells from barcodes added at one or more steps during the process. Single-cell RNA profiles determined by such methods can be useful for characterization of disease, drugs, toxins or environmental materials.[French]
L'invention concerne des procédés de séquençage de molécules d'ARN à partir de cellules uniques. Des étapes initiales sont exécutées sur des populations séparées d'ARN à partir de cellules individuelles, mais le séquençage et parfois d'autres étapes, telles que l'amplification, sont exécutées après le regroupement des populations à partir de cellules individuelles. Des séquences peuvent être déconvoluées vers leurs cellules d'origine à partir de codes à barres ajoutés à une ou plusieurs étapes pendant le processus. Des profils d'ARN unicellulaires déterminés selon de tels procédés peuvent être utiles pour la caractérisation d'une maladie, de médicaments, de toxines ou de matériaux environnementaux.