WO2025149998 - TOPICAL COMPOSITION COMPRISING CLASCOTERONE AND LATANOPROST FOR ALOPECIA

National phase entry is expected:
Publication Number WO/2025/149998
Publication Date 17.07.2025
International Application No. PCT/IB2025/050381
International Filing Date 13.01.2025
Title **
[English] TOPICAL COMPOSITION COMPRISING CLASCOTERONE AND LATANOPROST FOR ALOPECIA
[French] COMPOSITION TOPIQUE COMPRENANT DE LA CLASCOTÉRONE ET DU LATANOPROST POUR L'ALOPÉCIE
Applicants **
GLENMARK SPECIALTY S.A.
Inventors
OTAVKAR, Roopali
ABRAHAM, Jaya
BANGAR, Ganesh
DHUPPAD, Ulhas
KULKARNI, Abhay
GANDHI, Maulik
UDUPA, Venkatesh
PAWAR, Pramod
CHOPADE, Atul
Priority Data
202421002308   11.01.2024   IN
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting2227
EPO Filing, Examination, Granting11685
Japan Filing, Examination, Granting2368
South Korea Filing, Examination, Granting2511
USA Filing, Examination, Granting5140
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Total: 23,931
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Abstract[English] The present invention relates to the topical pharmaceutical composition comprising about 0.001% w/w to about 1% w/w latanoprost and about 1% w/w to about 15% w/w cortexolone-17α-propionate and a pharmaceutically acceptable vehicle comprising one or more solvent and process of its preparation. The invention further relates to the method wherein the composition is suitable for preventing and/or treating hair loss and/or stimulating hair growth. in patients suffering from alopecia, in particular androgenic alopecia (AGA).[French] La présente invention concerne la composition pharmaceutique topique comprenant environ 0,001 % p/p à environ 1 % p/p de latanoprost et environ 1 % p/p à environ 15 % p/p de cortexolone-17α-propionate et un véhicule pharmaceutiquement acceptable comprenant un ou plusieurs solvants et un procédé pour sa préparation. L'invention concerne en outre le procédé selon lequel la composition est appropriée pour prévenir et/ou traiter la chute des cheveux et/ou stimuler la pousse des cheveux chez les patients atteints d'alopécie, en particulier l'alopécie androgénique (AGA).