WO2026109941 - D-BHB (D-BETA-HYDROXYBUTYRATE) FOR USE IN THE TREATMENT OF LONG CHAIN FATTY ACID OXYDATION DEFICIENCY (LC-FAOD)

National phase entry is expected:
Publication Number WO/2026/109941
Publication Date 28.05.2026
International Application No. PCT/IB2025/000611
International Filing Date 21.11.2025
Title **
[English] D-BHB (D-BETA-HYDROXYBUTYRATE) FOR USE IN THE TREATMENT OF LONG CHAIN FATTY ACID OXYDATION DEFICIENCY (LC-FAOD)
[French] D-BHB (D-BÊTA-HYDROXYBUTYRATE) POUR UNE UTILISATION DANS LE TRAITEMENT D'UN DÉFICIT D'OXYDATION DES ACIDES GRAS À CHAÎNE LONGUE (LC-FAOD)
Applicants **
SOCIÉTÉ DES PRODUITS NESTLÉ S.A.
Inventors
LASSUEUR, Steve
RICHARD, Joy
DELERIVE, Philippe
Priority Data
63/724,190   22.11.2024   US
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting3776
EPO Filing, Examination, Granting16585
Japan Filing, Examination, Granting2276
South Korea Filing, Examination, Granting2322
USA Filing, Examination, Granting6090
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Total: 31,049
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Abstract[English] The present invention relates to the use of D-beta-hydroxybutyrate (D-BHB) in the treatment or dietary management of a Long-Chain Fatty Acid Oxidation Deficiency (LC-FAOD), for example, in the prevention and/or amelioration of one or more symptoms associated with LCFOAD. Additionally, the invention provides compositions comprising D-BHB as the active ingredient. These compositions may be formulated as pharmaceutical compositions or nutritional compositions, such as Foods for Special Medical Purposes (FSMPs).[French] La présente invention concerne l'utilisation de D-bêta-hydroxybutyrate (D-BHB) dans le traitement ou le suivi diététique d'un déficit d'oxydation des acides gras à chaîne longue (LC-FAOD), par exemple, dans la prévention et/ou l'atténuation d'un ou de plusieurs symptômes associés au LC-FAOD. De plus, l'invention concerne des compositions comprenant du D-BHB en tant que principe actif. Ces compositions peuvent être formulées sous la forme de compositions pharmaceutiques ou de compositions nutritionnelles, telles que des denrées alimentaires destinées à des fins médicales spéciales (DADFMS).