WO2025224506 - METHODS FOR REDUCING PLATELET DEGRADATION USING FCRN ANTAGONISTS

National phase entry is expected:
Publication Number WO/2025/224506
Publication Date 30.10.2025
International Application No. PCT/IB2025/000186
International Filing Date 22.04.2025
Title **
[English] METHODS FOR REDUCING PLATELET DEGRADATION USING FCRN ANTAGONISTS
[French] PROCÉDÉS DE RÉDUCTION DE LA DÉGRADATION DES PLAQUETTES À L'AIDE D'ANTAGONISTES DE FCRN
Applicants **
ARGENX BV
Inventors
ULRICHTS, Peter
GODAR, Marie
HULTBERG, Anna
MATTHIJSSENS, Filip
Priority Data
63/637,161   22.04.2024   US
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting3679
EPO Filing, Examination, Granting39956
Japan Filing, Examination, Granting3542
South Korea Filing, Examination, Granting4885
USA Filing, Examination, Granting16340
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Total: 68,402
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Abstract[English] Provided herein are methods of reducing platelet degradation in a subject in need thereof, such as a subject that has immune thrombocytopenia (ITP), using an antagonist of human neonatal Fc receptor (FcRn), which in certain embodiments is efgartigimod.[French] L'invention concerne des procédés de réduction de la dégradation des plaquettes chez un sujet en ayant besoin, tel qu'un sujet atteint d'une thrombocytopénie immunitaire (ITP), à l'aide d'un antagoniste du récepteur Fc néonatal humain (FcRn), qui dans certains modes de réalisation est l'efgartigimod.