WO2025133989 - SMYD MODULATORS AND USES THEREOF

National phase entry is expected:
Publication Number WO/2025/133989
Publication Date 26.06.2025
International Application No. PCT/IB2024/062924
International Filing Date 19.12.2024
Title **
[English] SMYD MODULATORS AND USES THEREOF
[French] MODULATEURS DE SMYD ET LEURS UTILISATIONS
Applicants **
ALT-BIO PTE. LTD.
Inventors
LIU, Jiwen
ZHU, Liusheng
Priority Data
63/612,845   20.12.2023   US
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting8075
EPO Filing, Examination, Granting171228
Japan Filing, Examination, Granting5101
South Korea Filing, Examination, Granting10768
USA Filing, Examination, Granting40590
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Total: 235,762

The term for entry into the National Phase has expired. This quotation is for informational purposes only

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Abstract[English] The present disclosure provides compounds or salts of Formula (A), (I) or (II), useful for epigenetic regulation via the modulation of SMYD. In another aspect, the present disclosure provides methods of modulating a SMYD protein via the administration of a compound or salt of Formula (A), (I) or (II), to a subject in need thereof.[French] La présente divulgation concerne des composés ou des sels de formule (A), (I) ou (II), utiles pour la régulation épigénétique par modulation de SMYD. Selon un autre aspect, la présente divulgation concerne des procédés de modulation d'une protéine SMYD par administration d'un composé ou d'un sel de formule (A), (I) ou (II), à un sujet en ayant besoin.

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