WO2025079025 - IDES-RAPAMYCIN CONJUGATE IN AAV GENE THERAPY

National phase entry is expected:
Publication Number WO/2025/079025
Publication Date 17.04.2025
International Application No. PCT/IB2024/059972
International Filing Date 11.10.2024
Title **
[English] IDES-RAPAMYCIN CONJUGATE IN AAV GENE THERAPY
[French] CONJUGUÉ IDES-RAPAMYCINE DANS UNE THÉRAPIE GÉNIQUE AAV
Applicants **
TAKEDA PHARMACEUTICAL COMPANY LIMITED
Inventors
KHAN, Tayeba
KENNISTON, Jon A.
NATARAJAN, Madhusudan
PALLISER, Deborah
LEE, Hong Myung
RICE, Elise
WATTERS, Alexander L.
PAPAIOANNOU, Nikolaos
Priority Data
63/590,195   13.10.2023   US
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting4271
EPO Filing, Examination, Granting46932
Japan Filing, Examination, Granting3663
South Korea Filing, Examination, Granting5150
USA Filing, Examination, Granting13990
MasterCard Visa
Total: 74,006

The term for entry into the National Phase has expired. This quotation is for informational purposes only

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Abstract[English] ., rapamycin, for immunosuppression in applications such as gene therapy. The present disclosure also provides methods of synthesis of conjugates and methods of conjugation (i.e. sortase-mediated conjugation) of payloads to IdeS or IdeZ for use in such applications.[French] La présente invention concerne également des procédés de synthèse de conjugués et des procédés de conjugaison (c'est-à-dire de conjugaison à médiation par sortase) de charges utiles à IdeS ou IdeZ à utiliser dans de telles applications.

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