WO2025041097 - IL-18 POLYPEPTIDES FUSED TO IMMUNE CELL ANTIGEN SPECIFIC BINDING POLYPEPTIDES AND USES THEREOF

National phase entry is expected:
Publication Number WO/2025/041097
Publication Date 27.02.2025
International Application No. PCT/IB2024/058222
International Filing Date 23.08.2024
Title **
[English] IL-18 POLYPEPTIDES FUSED TO IMMUNE CELL ANTIGEN SPECIFIC BINDING POLYPEPTIDES AND USES THEREOF
[French] POLYPEPTIDES IL-18 FUSIONNÉS À DES POLYPEPTIDES DE LIAISON SPÉCIFIQUES À UN ANTIGÈNE DE CELLULES IMMUNITAIRES ET LEURS UTILISATIONS
Applicants **
BRIGHT PEAK THERAPEUTICS AG
Inventors
PATTABIRAMAN, Vijaya Raghavan
KREFT, Bertolt
GOEPFERT, Arnaud
BORNERT, Olivier
CARRALOT, Jean-Philippe
MARTIN, Kea
Priority Data
63/534,311   23.08.2023   US
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting4764
EPO Filing, Examination, Granting48373
Japan Filing, Examination, Granting3833
South Korea Filing, Examination, Granting5809
USA Filing, Examination, Granting16840
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Total: 79,619

The term for entry into the National Phase has expired. This quotation is for informational purposes only

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Abstract[English] The present disclosure relates to fusion immunocytokines comprising antibodies or antigen binding fragments specific for immune cell associated antigens, such as PD-1, and IL- 18 polypeptides. Also provided herein are methods of treatment with and methods of manufacture of such fusion immunocytokines.[French] La présente divulgation concerne des immunocytokines de fusion comprenant des anticorps ou des fragments de liaison à l'antigène spécifiques d'antigènes associés à des cellules immunitaires, tels que PD-1, et des polypeptides IL-18. L'invention concerne également des méthodes de traitement et des procédés de fabrication de telles immunocytokines de fusion.