WO2025008797 - ORAL COMPOSITIONS COMPRISING TEMOZOLOMIDE OR LENALIDOMIDE

National phase entry:
Publication Number WO/2025/008797
Publication Date 09.01.2025
International Application No. PCT/IB2024/056585
International Filing Date 05.07.2024
Title **
[English] ORAL COMPOSITIONS COMPRISING TEMOZOLOMIDE OR LENALIDOMIDE
[French] COMPOSITIONS ORALES COMPRENANT DU TÉMOZOLOMIDE OU DU LÉNALIDOMIDE
Applicants **
SHORLA PHARMA LTD Questum Acceleration Centre Clonmel Co. Tipperary, E91 V329, IE
Inventors
CUNNINGHAM, Sharon Questum Acceleration Centre Clonmel Co. Tipperary, E91 V329, IE
RYAN, Orlaith Questum Acceleration Centre Clonmel Co. Tipperary, E91 V329, IE
DELANEY, Denis Questum Acceleration Centre Clonmel Co. Tipperary, E91 V329, IE
CLANCY, Maurice Questum Acceleration Centre Clonmel Co. Tipperary, E91 V329, IE
BAKER, Rod Bioedge Pharma Consultancy Limited 2 Minton Place, Victoria Road, Bicester Oxon OX26 6QB, GB
Priority Data
63/525,276   06.07.2023   US
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Quotation for National Phase entry

Country StagesTotal
China Filing1904
EPO Filing, Examination12989
Japan Filing590
South Korea Filing575
USA Filing, Examination7310
MasterCard Visa

Total: 23368

The term for entry into the National Phase has expired. This quotation is for informational purposes only

Abstract[English] The present disclosure provides a composition comprising temozolomide or lenalidomide, a medium chain triglyceride such as miglyol, silicon dioxide and a surfactant, wherein the composition optionally comprises an antioxidant and/or a flavoring agent, and wherein the temozolomide composition is a non-aqueous, preservative free suspension. Also provided is a method for treating cancer in a subject, such as a child or a subject suffering dysphagia and/or has difficulty swallowing.[French] La présente invention concerne une composition comprenant du témozolomide ou du lénalidomide, un triglycéride à chaîne moyenne tel que le miglyol, le dioxyde de silicium et un tensioactif, la composition comprenant éventuellement un antioxydant et/ou un agent aromatisant, et la composition de témozolomide étant une suspension sans conservateur non aqueuse. L'invention concerne également une méthode de traitement du cancer chez un sujet, tel qu'un enfant ou un sujet souffrant de dysphagie et/ou qui présente des difficultés à avaler.
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