WO2025008781 - METHOD OF PURIFICATION
National phase entry:
Publication Number
WO/2025/008781
Publication Date
09.01.2025
International Application No.
PCT/IB2024/056536
International Filing Date
04.07.2024
Title **
[English]
METHOD OF PURIFICATION
[French]
PROCÉDÉ DE PURIFICATION
Applicants **
CSL BEHRING AG
Wankdorfstrasse 10
3014 Bern, CH
Inventors
DOLLINGER, Peter
c/o CSL Innovation GmbH
Emil-von-Behring-Strasse 76
35041 Marburg, DE
HEERING, Dorota
c/o CSL Innovation GmbH
Emil-von-Behring-Strasse 76
35041 Marburg, DE
PAL CHOWDHURY, Nilanjan
c/o CSL Innovation GmbH
Emil-von-Behring-Strasse 76
35041 Marburg, DE
PILZ, Tessa
c/o CSL Innovation GmbH
Emil-von-Behring-Strasse 76
35041 Marburg, DE
Priority Data
23183376.5
04.07.2023
EP
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
| Number of Priorities | * |
| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
| Pages for Publication | * |
| Number of Pages with Drawings | * |
| Pages of Specification | * |
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| * | |
International Searching Authority |
EPO
* |
| Applicant's Legal Status |
Legal Entity
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| * | |
| * | |
| * | |
| * | |
| Entry into National Phase under |
Chapter I
* |
| Translation |
|
Recalculate
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Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing | 2171 | |
| EPO | Filing, Examination | 7467 | |
| Japan | Filing | 588 | |
| South Korea | Filing | 574 | |
| USA | Filing, Examination | 3610 |

Total: 14410 USD
The term for entry into the National Phase has expired. This quotation is for informational purposes only
Abstract[English]
The present disclosure relates to methods of isolating a protein-of-interest enriched solution, such as an immunoglobulin G (IgG), and a plurality of protein-of-interest depleted fractions from a protein mixture, such as plasma or a fraction thereof, using continuous chromatography. The present disclosure also relates to a continuous chromatography system for separating a protein-of-interest from a protein mixture, formulations and uses of the purified products thereof.[French]
La présente invention concerne des procédés d'isolement d'une solution enrichie en protéines d'intérêt, telle qu'une immunoglobuline G (IgG), et d'une pluralité de fractions appauvries en protéines d'intérêt à partir d'un mélange de protéines, tel qu'un plasma ou une fraction de celui-ci, à l'aide d'une chromatographie continue. La présente invention concerne également un système de chromatographie continue pour séparer une protéine d'intérêt d'un mélange de protéines, des formulations et des utilisations des produits purifiés de celui-ci.