WO2024261703 - BISPECIFIC ANTIBODIES FOR USE IN TREATMENT OF PATIENTS WITH XIAP DEFICIENCY OR CDC42 MUTATIONS

National phase entry:
Publication Number WO/2024/261703
Publication Date 26.12.2024
International Application No. PCT/IB2024/056062
International Filing Date 21.06.2024
Title **
[English] BISPECIFIC ANTIBODIES FOR USE IN TREATMENT OF PATIENTS WITH XIAP DEFICIENCY OR CDC42 MUTATIONS
[French] ANTICORPS BISPÉCIFIQUES DESTINÉS À ÊTRE UTILISÉS POUR TRAITER DES PATIENTS ATTEINTS D'UN DÉFICIT EN XIAP OU DE MUTATIONS DE CDC42
Applicants **
NOVARTIS AG
Inventors
BADMAN, Michael Keith
JUNGE, Guido
KIFFE, Michael
MCNAMARA, Elizabeth Akselrod
MEHES, Beata
SMITH, Rachel Claire
STEIN, Richard
WALDRON-LYNCH, Frank Derrick
Priority Data
63/509,905   23.06.2023   US
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting4568
EPO Filing, Examination, Granting51567
Japan Filing, Examination, Granting3758
South Korea Filing, Examination, Granting5324
USA Filing, Examination, Granting15640
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Total: 80,857

The term for entry into the National Phase has expired. This quotation is for informational purposes only

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Abstract[English] The invention relates to bivalent bispecific monoclonal antibodies (bbmAb) or variants thereof for use in the treatment or for use in alleviating the symptoms of an CDC42 mutation or XIAP deficiency based autoinflammation or disease in a subject in need thereof.[French] L'invention concerne des anticorps monoclonaux bispécifiques bivalents (bbmAb) ou des variants de ceux-ci destinés à être utilisés pour traiter ou pour soulager les symptômes d'une mutation de CDC42 ou d'une auto-inflammation ou d'une maladie liée à un déficit en XIAP chez un sujet en ayant besoin.