WO2024261703 - BISPECIFIC ANTIBODIES FOR USE IN TREATMENT OF PATIENTS WITH XIAP DEFICIENCY OR CDC42 MUTATIONS

National phase entry is expected:
Publication Number WO/2024/261703
Publication Date 26.12.2024
International Application No. PCT/IB2024/056062
International Filing Date 21.06.2024
Title **
[English] BISPECIFIC ANTIBODIES FOR USE IN TREATMENT OF PATIENTS WITH XIAP DEFICIENCY OR CDC42 MUTATIONS
[French] ANTICORPS BISPÉCIFIQUES DESTINÉS À ÊTRE UTILISÉS POUR TRAITER DES PATIENTS ATTEINTS D'UN DÉFICIT EN XIAP OU DE MUTATIONS DE CDC42
Applicants **
NOVARTIS AG Lichtstrasse 35 4056 Basel, CH
Inventors
BADMAN, Michael Keith Novartis Institutes for BioMedical Research, Inc. 250 Massachusetts Avenue Cambridge, Massachusetts 02139, US
JUNGE, Guido Novartis Pharma AG Lichtstrasse 35 4056 Basel, CH
KIFFE, Michael Novartis Pharma AG Lichtstrasse 35 4056 Basel, CH
MCNAMARA, Elizabeth Akselrod Novartis Institutes for BioMedical Research, Inc. 250 Massachusetts Avenue Cambridge, Massachusetts 02139, US
MEHES, Beata Novartis Pharma AG Lichtstrasse 35 4056 Basel, CH
SMITH, Rachel Claire 16 Woodlands Lane Leeds Yorkshire LS16 8GJ, GB
STEIN, Richard Novartis Pharma AG Lichtstrasse 35 4056 Basel, CH
WALDRON-LYNCH, Frank Derrick Ivy House Athboy Co Meath, C15 V38E, IE
Priority Data
63/509,905   23.06.2023   US
Application details
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Quotation for National Phase entry

Country StagesTotal
China Filing1139
EPO Filing, Examination6963
Japan Filing440
South Korea Filing543
USA Filing, Examination2360
MasterCard Visa

Total: 11445

Abstract[English] The invention relates to bivalent bispecific monoclonal antibodies (bbmAb) or variants thereof for use in the treatment or for use in alleviating the symptoms of an CDC42 mutation or XIAP deficiency based autoinflammation or disease in a subject in need thereof.[French] L'invention concerne des anticorps monoclonaux bispécifiques bivalents (bbmAb) ou des variants de ceux-ci destinés à être utilisés pour traiter ou pour soulager les symptômes d'une mutation de CDC42 ou d'une auto-inflammation ou d'une maladie liée à un déficit en XIAP chez un sujet en ayant besoin.
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