WO2024261696 - GLYCATED PROTEINS
National phase entry is expected:
Publication Number
WO/2024/261696
Publication Date
26.12.2024
International Application No.
PCT/IB2024/056046
International Filing Date
20.06.2024
Title **
[English]
GLYCATED PROTEINS
[French]
PROTÉINES GLYQUÉES
Applicants **
PNUVAX, INC.
134 Albert Street
Kingston, Ontario K7L 3V2, CA
DEHYROVAX BIOTECH INC.
15-8900 Bathurst Street
Vaughan, Ontario L4J 8A7, CA
Inventors
KAPLAN, Harvey
15-8900 Bathurst Street
Vaughan, Ontario L4J 8A7, CA
GERSON, Donald
134 Albert Street
Kingston, Ontario K7L 3V2, CA
Priority Data
63/509,161
20.06.2023
US
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
| Number of Priorities | * |
| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
| Pages for Publication | * |
| Number of Pages with Drawings | * |
| Pages of Specification | * |
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International Searching Authority |
CIPO
* |
| Applicant's Legal Status |
Legal Entity
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| * | |
| * | |
| * | |
| * | |
| Entry into National Phase under |
Chapter I
* |
| Translation |
|
Recalculate
* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing | 1273 | |
| EPO | Filing, Examination | 8545 | |
| Japan | Filing | 532 | |
| South Korea | Filing | 575 | |
| USA | Filing, Examination | 4635 |
Total: 15560 USD
Abstract[English]
Discloses herein are conjugates of a protein and one or more reducing sugars, wherein one, two, three or more target amino groups of the protein are glycated. Also disclosed are methods for the preparation of the glycated protein. Conjugates having one or more ketoamine linkages are efficiently prepared through the reaction between the protein and reducing sugars and exhibit desirable pharmaceutical properties.[French]
L'invention concerne des conjugués d'une protéine et d'un ou de plusieurs sucres réducteurs, un, deux, trois groupes amino cibles ou plus de la protéine étant glyqués. L'invention concerne également des procédés de préparation de la protéine glyquée. Des conjugués ayant une ou plusieurs liaisons cétoamines sont préparés efficacement par réaction entre la protéine et des sucres réducteurs et présentent des propriétés pharmaceutiques souhaitées.