WO2024261641 - TREATMENT OF PRIMARY CTLA-4 CHECKPOINT RELATED IMMUNODEFICIENCIES WITH 1H-INDOLE-3-CARBOXALDEHYDE OR 1-METHYLINDOLE-3-CARBOXYLIC ACID

National phase entry:
Publication Number WO/2024/261641
Publication Date 26.12.2024
International Application No. PCT/IB2024/055943
International Filing Date 18.06.2024
Title **
[English] TREATMENT OF PRIMARY CTLA-4 CHECKPOINT RELATED IMMUNODEFICIENCIES WITH 1H-INDOLE-3-CARBOXALDEHYDE OR 1-METHYLINDOLE-3-CARBOXYLIC ACID
[French] TRAITEMENT D'IMMUNODÉFICIENCES ASSOCIÉES AU POINT DE CONTRÔLE CTLA-4 PRIMAIRE AVEC DE L'ACIDE 1H-INDOLE-3-CARBOXALDÉHYDE OU DE L'ACIDE 1-MÉTHYLINDOLE-3-CARBOXYLIQUE
Applicants **
ADIENNE PHARMA & BIOTECH SA Via Zurigo N. 46 6900 Lugano, CH
Inventors
DI NARO, Antonio Francesco Via San Bartolomee 7 6922 Morcote, CH
GIOVAGNOLI, Stefano 1 Via del Liceo 06123 Perugia, IT
PUCCETTI, Matteo 1 Via del Liceo 06123 Perugia, IT
PARIANO, Marilena 1 P.le Lucio Severi 06123 Perugia, IT
Priority Data
63/509,223   20.06.2023   US
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Quotation for National Phase entry

Country StagesTotal
China Filing1987
EPO Filing, Examination10275
Japan Filing593
South Korea Filing575
USA Filing, Examination4760
MasterCard Visa

Total: 18190

The term for entry into the National Phase has expired. This quotation is for informational purposes only

Abstract[English] The present disclosure is directed to a method of treating a CTLA-4 checkpoint related immunodeficiency by administering a therapeutically effective amount of a pharmaceutical composition comprising 1H-indole-3-carboxaldehyde (3-IAld) or 1-methylindole-3-carboxylic acid.[French] La présente invention concerne une méthode de traitement d'une immunodéficience associée au point de contrôle CTLA-4 par administration d'une quantité thérapeutiquement efficace d'une composition pharmaceutique comprenant de l'acide 1H-indole-3-carboxaldéhyde (3-IAld) ou de l'acide 1-méthylindole-3-carboxylique.
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