WO2024252367 - NOVEL GLP-1/GIP DUAL AND GLP-1/GCG DUAL RECEPTOR AGONISTS

National phase entry is expected:
Publication Number WO/2024/252367
Publication Date 12.12.2024
International Application No. PCT/IB2024/055620
International Filing Date 07.06.2024
Title **
[English] NOVEL GLP-1/GIP DUAL AND GLP-1/GCG DUAL RECEPTOR AGONISTS
[French] NOUVEAUX AGONISTES DU RÉCEPTEUR DOUBLE GLP-1/GIP ET GLP-1/GCG
Applicants **
SUN PHARMACEUTICAL INDUSTRIES LIMITED SUN HOUSE, PLOT NO. 201 B/1, WESTERN EXPRESS HIGHWAY, GOREGAON (E) Mumbai 400063, IN
Inventors
THENNATI, Rajamannar 17A, 17B Pratham Avenue Akota Road. Opp. Taj Vivanta, Akota Vadodara 390020, IN
BURADE, Vinod Sampatrao C-402, Kamalanjali Apt. B/H Hdfc Bank, Akota Road, Akota Vadodara 390020, IN
NATARAJAN, Muthukumaran Villa No. 82, San Tropez, Madrid County Opposite to Ashapuri Mataji Mandir, Bhayli-Station Road, Bhayli Vadodara 391410, IN
JOSHI, Dhiren Rameshchandra 203, Saundarya Greens-2 Canal Road, T.P. 13, Chhani Jakat Naka Vadodara 390024, IN
GANDHI, Manish Harendraprasad B-33 Devashish Duplex Waghodia road Nr Manan park Vadodara 390019, IN
JIVANI, Chandulal Thakarshibhai D-74 Balgopal Society Nr Darbar chokadi. Manjalpur Vadodara 390011, IN
TIWARI, Abhishek 1535-A, R. K. Puram Sector A Kota 324005, IN
SONI, Krunal Harishbhai A-18, Palm Green Residency, Ajwa-Waghodiya Ring Road Vadodara 390019, IN
MARU, Alpeshbhai Balabhai Juno gramya vistar, Rupavati, Tal: Gariyadhar Bhavnagar 364505, IN
DIXIT, Pankaj Vinodrao R33, Near Radha Rani Appartments Silicon City Indore 452012, IN
PATELIYA, Bharatbhai Balabhai C/303, Shree Radhe Shyam, Opp The Oakwood, Vasna Bhayli Road, Bhayli Vadodara 391410, IN
NAGARAJA, Ravishankara Madavati A-21, Nilamber Oriens Opposite Shyamal Enclave, Sun Pharma Road, Tandalja Vadodara 390012, IN
Priority Data
202321039646   09.06.2023   IN
Application details
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Entry into National Phase under
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Quotation for National Phase entry

Country StagesTotal
China Filing1878
EPO Filing, Examination10576
Japan Filing532
South Korea Filing575
USA Filing, Examination14235
MasterCard Visa

Total: 27796

Abstract[English] The present disclosure provides GLP-1/GIP and GLP-1/GCG dual receptor agonists comprising incretin analog polypeptides and use thereof in the treatment or prevention of Type 2 diabetes mellitus (T2DM), hyperlipidemia/dyslipidemia, metabolic syndromes, metabolic dysfunction-associated steatotic liver disease (MASLD), metabolic dysfunction- associated steatohepatitis (MASH), neurodegenerative disorders, fibrosis, cardiovascular risks, and/or obesity.[French] La présente divulgation concerne des agonistes doubles du récepteur GLP-1/GIP et GLP-1/GCG comprenant des polypeptides analogues d'incrétine et leur utilisation dans le traitement ou la prévention du diabète sucré de type 2 (T2DM), de l'hyperlipidémie/dyslipidémie, des syndromes métaboliques, de la stéatose hépatique associée à un dysfonctionnement métabolique (MASLD), de la stéatohépatite associée à un dysfonctionnement métabolique (MASH), de troubles neurodégénératifs, de la fibrose, des risques cardiovasculaires et/ou de l'obésité.
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