WO2024236504 - SEQUENCES AND METHODS FOR DELIVERY OF DNA AND RNA

National phase entry is expected:
Publication Number WO/2024/236504
Publication Date 21.11.2024
International Application No. PCT/IB2024/054730
International Filing Date 15.05.2024
Title **
[English] SEQUENCES AND METHODS FOR DELIVERY OF DNA AND RNA
[French] SÉQUENCES ET PROCÉDÉS D'ADMINISTRATION D'ADN ET D'ARN
Applicants **
TAKEDA PHARMACEUTICAL COMPANY LIMITED
Inventors
CONDORI, Jose
CHOI, Vivian
Priority Data
63/502,389   15.05.2023   US
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting3947
EPO Filing, Examination, Granting29625
Japan Filing, Examination, Granting3277
South Korea Filing, Examination, Granting4119
USA Filing, Examination, Granting17640
MasterCard Visa
Total: 58,608

The term for entry into the National Phase has expired. This quotation is for informational purposes only

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Abstract[English] The present disclosure relates to sequences and methods for delivery of DNA and RNA using, for example, DNA nuclear targeting sequences (DTSs). These sequences provide more efficient delivery of target DNA and RNA into cells. These sequences are also particularly effective for targeting liver cells, for example, for treatment of inherited liver and systemic disorders, as well as acquired genetic disorders, and also serve as a treatment method for numerous diseases and disorders.[French] La présente invention concerne des séquences et des procédés d'administration d'ADN et d'ARN à l'aide, par exemple, de séquences de ciblage nucléaire d'ADN (DTS). Ces séquences permettent une administration plus efficace d'ADN et d'ARN cibles dans des cellules. Ces séquences sont également particulièrement efficaces pour cibler des cellules hépatiques, par exemple, pour le traitement de troubles hépatiques et systémiques hérités, ainsi que des troubles génétiques acquis, et servent également de procédé de traitement pour de nombreuses maladies et troubles.

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