WO2025210386 - PHARMACEUTICAL COMPOSITIONS FOR STAINING MEMBRANES AND OTHER BIOLOGICAL STRUCTURES USING A NATURAL OR SYNTHETIC CBD-BASED VITAL DYE ISOLATED AND/OR ASSOCIATED WITH OTHER DYES FOR VITREORETINAL SURGERY
National phase entry is expected:
Publication Number
WO/2025/210386
Publication Date
09.10.2025
International Application No.
PCT/IB2024/053301
International Filing Date
04.04.2024
Title **
[English]
PHARMACEUTICAL COMPOSITIONS FOR STAINING MEMBRANES AND OTHER BIOLOGICAL STRUCTURES USING A NATURAL OR SYNTHETIC CBD-BASED VITAL DYE ISOLATED AND/OR ASSOCIATED WITH OTHER DYES FOR VITREORETINAL SURGERY
[French]
COMPOSITIONS PHARMACEUTIQUES POUR COLORER DES MEMBRANES ET D'AUTRES STRUCTURES BIOLOGIQUES À L'AIDE D'UN COLORANT VITAL À BASE DE CBD NATUREL OU SYNTHÉTIQUE ISOLÉ ET/OU ASSOCIÉ À D'AUTRES COLORANTS POUR UNE CHIRURGIE VITRÉO-RÉTINIENNE
Applicants **
VICADIA LDA
Inventors
SOUSA-MARTINS, Diogo
Priority Data
119355
01.04.2024
PT
Application details
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International Searching Authority |
EPO
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| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
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| Type of Assignment |
The Standard Agent's Assignment
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| Applicant's Legal Status |
Legal Entity
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| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| Translation |
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* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 2054 | |
| EPO | Filing, Examination, Granting | 8701 | |
| Japan | Filing, Examination, Granting | 2217 | |
| South Korea | Filing, Examination, Granting | 2084 | |
| USA | Filing, Examination, Granting | 4740 |
Total:
19,796
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Abstract[English]
The present invention describes the use of a pharmaceutical compositions for dyeing or staining membranes and other biological structures using a natural or synthetic CBD-based vital dye isolated and/or associated with other dyes, namely BBG and/or TB, as a promising approach during surgical or medical procedures, such as vitreoretinal. The use of such compounds for the preparation of dyeing or staining compositions in order to facilitate their identification and biomolecular membrane composition, results in the visualization of different types of ocular membranes and tissues along with the cellular and tissue protection from damage induced by the exposition to surgical light. The present invention describes the entirety process, since the production of the composition purpose along with formulation and studies conducted, until the purport method for staining biological membranes and structures to improve their adequate identification and manipulation, responding to the challenged presented by the complexity of the surgical procedure mainly chromovitrectomy.[French]
La présente invention concerne l'utilisation d'une composition pharmaceutique pour teindre ou colorer des membranes et d'autres structures biologiques à l'aide d'un colorant vital à base de CBD naturel ou synthétique isolé et/ou associé à d'autres colorants, à savoir le BBG et/ou le TB, en tant qu'approche prometteuse pendant des procédures chirurgicales ou médicales, comme la chirurgie vitréo-rétinienne. L'utilisation de tels composés pour la préparation de compositions tinctoriales ou de coloration afin de faciliter leur identification et la composition de leur membrane biomoléculaire, permet de visualiser différents types de membranes et de tissus oculaires ainsi que la protection cellulaire et tissulaire contre les dommages induits par l'exposition à la lumière chirurgicale. La présente invention décrit l'ensemble du processus, depuis la production de la composition, sa formulation et les études menées, jusqu'à la méthode de coloration des membranes et des structures biologiques pour améliorer leur identification et leur manipulation adéquates, répondant ainsi au défi posé par la complexité de la procédure chirurgicale, principalement la chromo-vitrectomie.