WO2024201406 - METHODS OF TREATING SPINAL CORD INJURIES WITH ALTERNATING ELECTRIC FIELDS
National phase entry is expected:
Publication Number
WO/2024/201406
Publication Date
03.10.2024
International Application No.
PCT/IB2024/053094
International Filing Date
29.03.2024
Title **
[English]
METHODS OF TREATING SPINAL CORD INJURIES WITH ALTERNATING ELECTRIC FIELDS
[French]
MÉTHODES DE TRAITEMENT DE LÉSIONS DE LA MOELLE ÉPINIÈRE AVEC DES CHAMPS ÉLECTRIQUES ALTERNATIFS
Applicants **
NOVOCURE GMBH
Park 6
CH-6039 Root D4, CH
Inventors
AVIGDOR, Lilach
NOVOCURE GMBH - Topaz Building, 4th Floor
MATAM Center, P.O. Box 15022
Sha'ar HaCarmel
31905 Haifa, IL
Priority Data
63/493,383
31.03.2023
US
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
| Number of Priorities | * |
| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
| Pages for Publication | * |
| Number of Pages with Drawings | * |
| Pages of Specification | * |
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International Searching Authority |
EPO
* |
| Applicant's Legal Status |
Legal Entity
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| * | |
| * | |
| * | |
| * | |
| Entry into National Phase under |
Chapter I
* |
| Translation |
|
Recalculate
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Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing | 1016 | |
| EPO | Filing, Examination | 4634 | |
| Japan | Filing | 533 | |
| South Korea | Filing | 576 | |
| USA | Filing, Examination | 2635 |
Total: 9394 USD
The term for entry into the National Phase has expired. This quotation is for informational purposes only
Abstract[English]
Disclosed are methods of treating a subject having a spinal cord injury comprising applying an alternating electric field, at a frequency for a period of time, to a target site of the subject. Disclosed herein are methods of increasing N-cadherin expression in a subject having spinal cord injury comprising applying alternating electric fields, at a frequency for a period of time, to a target site of the subject, thereby increasing N-cadherin expression at the target site in the subject. Disclosed are methods of increasing neuronal connection, axon regeneration, neuronal protection, and/or neuronal differentiation in a subject having a spinal cord injury comprising applying alternating electric fields, at a frequency for a period of time, to a target site of the subject.[French]
La divulgation concerne des méthodes de traitement d'un sujet ayant une lésion de la moelle épinière comprenant l'application d'un champ électrique alternatif, à une fréquence pendant une période de temps, à un site cible du sujet. La présente divulgation concerne des méthodes d'augmentation de l'expression de N-cadhérine chez un sujet ayant une lésion de la moelle épinière comprenant l'application de champs électriques alternatifs, à une fréquence pendant une période de temps, à un site cible du sujet, ce qui permet d'augmenter l'expression de N-cadhérine au niveau du site cible chez le sujet. La divulgation concerne des méthodes d'augmentation de la connexion neuronale, de la régénération d'axone, de la protection neuronale et/ou de la différenciation neuronale chez un sujet ayant une lésion de la moelle épinière comprenant l'application de champs électriques alternatifs, à une fréquence pendant une période de temps, à un site cible du sujet.