WO2024170976 - CODON OPTIMIZED POLYNUCLEOTIDE ENCODING HUMAN FACTOR IX

National phase entry is expected:
Publication Number WO/2024/170976
Publication Date 22.08.2024
International Application No. PCT/IB2024/050692
International Filing Date 25.01.2024
Title **
[English] CODON OPTIMIZED POLYNUCLEOTIDE ENCODING HUMAN FACTOR IX
[French] POLYNUCLÉOTIDE À CODON OPTIMISÉ CODANT POUR LE FACTEUR IX HUMAIN
Applicants **
INTAS PHARMACEUTICALS LTD. Corporate House, Near Sola Bridge, S. G. Highway, Thaltej, Ahmedabad - 380054, Gujarat, IN
Inventors
MISHRA, Niraj Intas Pharmaceuticals Limited – Biopharma Division, Plot No: 423/P/A/GIDC, Vill: Moraiya Sarkhej-Bavla Highway, Ta:Sanand, Ahmedabad-382213. Gujarat, IN
BASAK, Shashwati Intas Pharmaceuticals Limited – Biopharma Division, Plot No: 423/P/A/GIDC, Vill: Moraiya Sarkhej-Bavla Highway, Ta:Sanand, Ahmedabad-382213. Gujarat, IN
Priority Data
202321011083   18.02.2023   IN
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Quotation for National Phase entry

Country StagesTotal
China Filing972
EPO Filing, Examination7067
Japan Filing591
South Korea Filing575
USA Filing, Examination4510
MasterCard Visa

Total: 13715

The term for entry into the National Phase has expired. This quotation is for informational purposes only

Abstract[English] The present invention relates to polynucleotide comprising codon optimized nucleotide encoding human Factor IX protein. The method of treatment of hemophilia by administering polynucleotide comprising codon optimized nucleotide encoding human Factor IX protein wherein, the activity of human Factor IX of the present invention is higher than the wild type human Factor IX.[French] La présente invention concerne un polynucléotide comprenant un nucléotide à codon optimisé codant pour la protéine du facteur IX humain. Le procédé de traitement de l'hémophilie consiste à administrer un polynucléotide comprenant un nucléotide à codon optimisé codant pour la protéine du facteur IX humain, l'activité du facteur IX humain de la présente invention étant supérieure à celle du facteur IX humain de type sauvage.
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