WO2024157194 - METHODS AND ASSAYS FOR OFF-TARGET ANALYSIS

National phase entry is expected:
Publication Number WO/2024/157194
Publication Date 02.08.2024
International Application No. PCT/IB2024/050681
International Filing Date 25.01.2024
Title **
[English] METHODS AND ASSAYS FOR OFF-TARGET ANALYSIS
[French] PROCÉDÉS ET DOSAGES POUR ANALYSE HORS CIBLE
Applicants **
CRISPR THERAPEUTICS AG
Inventors
CHAUDHARI,, Hemangi
PENTERMAN, Jon
KULMAN, John
Priority Data
63/481,529   25.01.2023   US
63/481,547   25.01.2023   US
Application details
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Entry into National Phase under
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Translation

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Quotation for National Phase entry

Country StagesTotal
China Filing3178
EPO Filing, Examination31154
Japan Filing590
South Korea Filing606
USA Filing, Examination13360
MasterCard Visa
Total: 48,888

The term for entry into the National Phase has expired. This quotation is for informational purposes only

Abstract[English] The present disclosure provides methods, assays, nucleic acid libraries, compositions, kits and systems for assessing RNA-guided endonucleases including their on-target and/or off-target activities, and for generating off-target profiles for RNA-guided endonucleases.[French] La présente invention concerne des procédés, des dosages, des banques d'acides nucléiques, des compositions, des kits et des systèmes permettant d'évaluer les endonucléases guidées par l'ARN, y compris leurs activités sur cible et/ou hors cible, et de générer des profils hors cible pour les endonucléases guidées par ARN.

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