WO2024157194 - METHODS AND ASSAYS FOR OFF-TARGET ANALYSIS
National phase entry is expected:
Publication Number
WO/2024/157194
Publication Date
02.08.2024
International Application No.
PCT/IB2024/050681
International Filing Date
25.01.2024
Title **
[English]
METHODS AND ASSAYS FOR OFF-TARGET ANALYSIS
[French]
PROCÉDÉS ET DOSAGES POUR ANALYSE HORS CIBLE
Applicants **
CRISPR THERAPEUTICS AG
Inventors
CHAUDHARI,, Hemangi
PENTERMAN, Jon
KULMAN, John
Priority Data
63/481,529
25.01.2023
US
63/481,547
25.01.2023
US
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
| Number of Priorities | * |
| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
| Pages for Publication | * |
| Number of Pages with Drawings | * |
| Pages of Specification | * |
| * | |
| * | |
International Searching Authority |
EPO
* |
| Applicant's Legal Status |
Legal Entity
* |
| * | |
| * | |
| * | |
| * | |
| Entry into National Phase under |
Chapter I
* |
| Translation |
|
* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing | 3178 | |
| EPO | Filing, Examination | 31154 | |
| Japan | Filing | 590 | |
| South Korea | Filing | 606 | |
| USA | Filing, Examination | 13360 |

Total:
48,888
The term for entry into the National Phase has expired. This quotation is for informational purposes only
Abstract[English]
The present disclosure provides methods, assays, nucleic acid libraries, compositions, kits and systems for assessing RNA-guided endonucleases including their on-target and/or off-target activities, and for generating off-target profiles for RNA-guided endonucleases.[French]
La présente invention concerne des procédés, des dosages, des banques d'acides nucléiques, des compositions, des kits et des systèmes permettant d'évaluer les endonucléases guidées par l'ARN, y compris leurs activités sur cible et/ou hors cible, et de générer des profils hors cible pour les endonucléases guidées par ARN.