WO2024157194 - METHODS AND ASSAYS FOR OFF-TARGET ANALYSIS

National phase entry is expected:
Publication Number WO/2024/157194
Publication Date 02.08.2024
International Application No. PCT/IB2024/050681
International Filing Date 25.01.2024
Title **
[English] METHODS AND ASSAYS FOR OFF-TARGET ANALYSIS
[French] PROCÉDÉS ET DOSAGES POUR ANALYSE HORS CIBLE
Applicants **
CRISPR THERAPEUTICS AG Baarerstrasse 14 6300 Zug, CH
Inventors
CHAUDHARI,, Hemangi 105 West First Street South Boston, Massachusetts 02127, US
PENTERMAN, Jon 105 West First Street South Boston, Massachusetts 02127, US
KULMAN, John 105 West First Street South Boston, Massachusetts 02127, US
Priority Data
63/481,529   25.01.2023   US
63/481,547   25.01.2023   US
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Quotation for National Phase entry

Country StagesTotal
China Filing3094
EPO Filing, Examination30019
Japan Filing589
South Korea Filing607
USA Filing, Examination13285
MasterCard Visa

Total: 47594

The term for entry into the National Phase has expired. This quotation is for informational purposes only

Abstract[English] The present disclosure provides methods, assays, nucleic acid libraries, compositions, kits and systems for assessing RNA-guided endonucleases including their on-target and/or off-target activities, and for generating off-target profiles for RNA-guided endonucleases.[French] La présente invention concerne des procédés, des dosages, des banques d'acides nucléiques, des compositions, des kits et des systèmes permettant d'évaluer les endonucléases guidées par l'ARN, y compris leurs activités sur cible et/ou hors cible, et de générer des profils hors cible pour les endonucléases guidées par ARN.
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