WO2025078880 - MITOCHONDRIA-TARGETED ANTIOXIDANTS FOR USE IN THE TREATMENT OF CELL BALLOOONING-ASSOCIATED DISEASES, SUCH AS NON-ALCOHOLIC FATTY LIVER DISEASE (NAFLD) AND NON-ALCOHOLIC STEATOHEPATITIS (NASH)
National phase entry:
Publication Number
WO/2025/078880
Publication Date
17.04.2025
International Application No.
PCT/IB2024/000569
International Filing Date
11.10.2024
Title **
[English]
MITOCHONDRIA-TARGETED ANTIOXIDANTS FOR USE IN THE TREATMENT OF CELL BALLOOONING-ASSOCIATED DISEASES, SUCH AS NON-ALCOHOLIC FATTY LIVER DISEASE (NAFLD) AND NON-ALCOHOLIC STEATOHEPATITIS (NASH)
[French]
ANTIOXYDANTS CIBLANT LES MITOCHONDRIES DESTINÉS À ÊTRE UTILISÉS DANS LE TRAITEMENT DE MALADIES ASSOCIÉES À LA BALLONISATION CELLULAIRE, COMME LA STÉATO-HÉPATOPATHIE NON ALCOOLIQUE (NAFLD) ET LA STÉATOHÉPATITE NON ALCOOLIQUE (NASH)
Applicants **
MITOTECH S.A.
Inventors
SKULACHEV, Maxim
PETROV, Anton
Priority Data
63/543,668
11.10.2023
US
Application details
| Total Number of Claims/PCT | * |
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| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
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International Searching Authority |
EPO
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| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
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| Type of Assignment |
The Standard Agent's Assignment
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| Applicant's Legal Status |
Legal Entity
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| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| Translation |
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* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 2477 | |
| EPO | Filing, Examination, Granting | 15015 | |
| Japan | Filing, Examination, Granting | 2553 | |
| South Korea | Filing, Examination, Granting | 2888 | |
| USA | Filing, Examination, Granting | 6340 |
Total:
29,273
The term for entry into the National Phase has expired. This quotation is for informational purposes only
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Abstract[English]
Methods and compositions for treating and preventing cell ballooning and other diseases or medical conditions are provided. The diseases or medical conditions are characterized by cell degeneration or cell death as a part of the disease pathogenesis. Cell ballooning is a condition associated with storage of excess fat in the liver. nutritional or biochemical imbalance, damage to mitochondria, ATP depletion, or virus infection. A mitochondrially targeted antioxidant compound is administered to a subject in need thereof, whereby excess fat is metabolized.[French]
L'invention concerne des méthodes et des compositions pour traiter et prévenir une ballonisation cellulaire et d'autres maladies ou pathologies médicales. Les maladies ou les pathologies médicales sont caractérisées par une dégénérescence cellulaire ou une mort cellulaire en tant que partie de la pathogenèse de la maladie. La ballonisation cellulaire est une pathologie associée au stockage d'excès de graisse dans le foie, à un déséquilibre nutritionnel ou biochimique, à un endommagement des mitochondries, à une déplétion d'ATP ou à une infection virale. Un composé antioxydant ciblant les mitochondries est administré à un sujet en ayant besoin, l'excès de graisse étant ainsi métabolisé.