WO2024175997 - WATER-SOLUBLE CHLOROPHYLL PROTEIN AS EFFICIENT PHOTOSENSITIZER FOR CANCER PHOTODYNAMIC THERAPY
National phase entry:
Publication Number
WO/2024/175997
Publication Date
29.08.2024
International Application No.
PCT/IB2024/000091
International Filing Date
20.02.2024
Title **
[English]
WATER-SOLUBLE CHLOROPHYLL PROTEIN AS EFFICIENT PHOTOSENSITIZER FOR CANCER PHOTODYNAMIC THERAPY
[French]
PROTÉINE WSCP (WATER-SOLUBLE CHLOROPHYLL PROTEIN) EN TANT QUE PHOTOSENSIBILISATEUR EFFICACE POUR UNE THÉRAPIE PHOTODYNAMIQUE DU CANCER
Applicants **
THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
Inventors
TONG, Rongbiao
SUN, Fei
LIANG, Lixin
WANG, Wenjun
XU, Yingjie
Priority Data
63/485,928
20.02.2023
US
Application details
| Total Number of Claims/PCT | * |
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International Searching Authority |
CNIPA
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| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
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| Type of Assignment |
The Standard Agent's Assignment
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| Applicant's Legal Status |
Legal Entity
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| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| Translation |
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Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 2300 | |
| EPO | Filing, Examination, Granting | 15307 | |
| Japan | Filing, Examination, Granting | 2405 | |
| South Korea | Filing, Examination, Granting | 2545 | |
| USA | Filing, Examination, Granting | 5340 |
Total:
27,897
The term for entry into the National Phase has expired. This quotation is for informational purposes only
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Abstract[English]
Provided is a safe and effective photosensitizer that expands the clinical use of photodynamic therapy (PDT) as a non-invasive cancer treatment. Specifically, Provided are methods of using water-soluble chlorophyll protein (WSCP) as a new photosensitizer for cancer phototherapy. Advantageously, WSCP is stable, non-toxic, and biocompatible while generating reactive oxygen species, making it useful for deep-tissue PDT.[French]
La présente invention concerne un photosensibilisateur sûr et efficace qui étend l'utilisation clinique d'une thérapie photodynamique (PDT) en tant que traitement anticancéreux non invasif. Spécifiquement, la présente invention concerne des procédés d'utilisation de la protéine WSCP (water-soluble chlorophyll protein) en tant que nouveau photosensibilisateur pour la photothérapie du cancer. De manière avantageuse, la protéine WSCP est stable, non toxique et biocompatible tout en générant des espèces réactives de l'oxygène, ce qui la rend utile pour la PDT dans les tissus profonds.