WO2024141957 - DETERMINING A FREQUENCY FOR TUMOR TREATING FIELDS (TTFIELDS) THERAPY BASED ON TESTS PERFORMED ON THE TUMOR CELLS
National phase entry:
Publication Number
WO/2024/141957
Publication Date
04.07.2024
International Application No.
PCT/IB2023/063296
International Filing Date
28.12.2023
Title **
[English]
DETERMINING A FREQUENCY FOR TUMOR TREATING FIELDS (TTFIELDS) THERAPY BASED ON TESTS PERFORMED ON THE TUMOR CELLS
[French]
DÉTERMINATION D'UNE FRÉQUENCE POUR UN TRAITEMENT PAR CHAMPS DE TRAITEMENT DE TUMEURS (TTFIELDS) SUR LA BASE DE TESTS EFFECTUÉS SUR LES CELLULES TUMORALES
Applicants **
NOVOCURE GMBH
Neuhofstrasse 21
6340 Baar, CH
Inventors
WASSERMAN, Yoram
c/o Novocure GmbH, Topaz Building, 4th Floor
MATAM Center, PO Box 15022, Sha'ar HaCarmel
31905 Haifa, IL
BEN-TOV KUPERBERG, Mor
c/o Novocure GmbH, Topaz Building, 4th Floor
MATAM Center, PO Box 15022, Sha'ar HaCarmel
31905 Haifa, IL
Priority Data
63/435,900
29.12.2022
US
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
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| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
| Pages for Publication | * |
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| Pages of Specification | * |
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International Searching Authority |
EPO
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| Applicant's Legal Status |
Legal Entity
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| Entry into National Phase under |
Chapter I
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| Translation |
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Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing | 1256 | |
| EPO | Filing, Examination | 6301 | |
| Japan | Filing | 586 | |
| South Korea | Filing | 574 | |
| USA | Filing, Examination | 2710 |
Total: 11427 USD
The term for entry into the National Phase has expired. This quotation is for informational purposes only
Abstract[English]
Cancer treatment using TTFields (Tumor Treating Fields) can be customized to each individual subject by extracting cancer cells from the subject's body. Alternating electric fields are then applied to the extracted cells at different frequencies, and voltage measurements are obtained from the cells under two different conditions at each of the different frequencies. These voltage measurements can then be used to determine what frequency will provide the largest gradient at the cleavage furrow when similar cells divide, which will in turn increase the efficacy of the TTFields. Treatment using TTFields can then proceed at the determined frequency.[French]
Le traitement du cancer à l'aide de champs TTFields (champs de traitement de tumeurs) peut être personnalisé pour chaque sujet individuel par prélèvement de cellules cancéreuses sur le corps du sujet. Des champs électriques alternatifs sont ensuite appliqués aux cellules extraites à différentes fréquences, et des mesures de tension sont obtenues à partir des cellules dans deux conditions différentes à chacune des fréquences différentes. Ces mesures de tension peuvent ensuite être utilisées pour déterminer la fréquence qui assurera le gradient le plus grand au niveau du sillon de clivage lorsque des cellules similaires se divisent, ce qui aura pour conséquence d'augmenter l'efficacité des champs TTFields. Le traitement à l'aide de champs TTFields peut ensuite se dérouler à la fréquence déterminée.