WO2024121697 - DE NOVO SEQUENCING OF DNA
National phase entry:
Publication Number
WO/2024/121697
Publication Date
13.06.2024
International Application No.
PCT/IB2023/062157
International Filing Date
02.12.2023
Title **
[English]
DE NOVO SEQUENCING OF DNA
[French]
SÉQUENÇAGE DE NOVO D'ADN
Applicants **
DH TECHNOLOGIES DEVELOPMENT PTE. LTD.
Inventors
BABA, Takashi
KARASAWA, Kaoru
Priority Data
63/386,414
07.12.2022
US
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
| Number of Priorities | * |
| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
| Pages for Publication | * |
| Number of Pages with Drawings | * |
| Pages of Specification | * |
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| Number of Office Actions | * |
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International Searching Authority |
EPO
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| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
* |
| Type of Assignment |
The Standard Agent's Assignment
* |
| Applicant's Legal Status |
Legal Entity
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| * | |
| * | |
| * | |
| * | |
| * | |
| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| Translation |
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* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 2181 | |
| EPO | Filing, Examination, Granting | 9176 | |
| Japan | Filing, Examination, Granting | 2211 | |
| South Korea | Filing, Examination, Granting | 2079 | |
| USA | Filing, Examination, Granting | 5340 |
Total:
20,987
The term for entry into the National Phase has expired. This quotation is for informational purposes only
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Abstract[English]
A first product ion mass spectrum of a nucleic acid analyzed using a CID method is received. Also, a second product ion mass spectrum of the nucleic acid analyzed using a radical-induced dissociation method is received. Peak m/z values of the first spectrum, peak m/z values of the second spectrum, and an m/z value of a precursor ion of the nucleic acid are converted to a single charge. A peak m/z value of the first spectrum is determined that differs from a peak m/z value of the second spectrum by a mass value of a structure within the nucleic acid the radical-induced dissociation method is known to not be able to dissociate and the CID method is known to be able to dissociate. The structure includes a phosphorus atom and an optionally substituted 5 -membered ring containing an oxygen.[French]
Un premier spectre de masse d'ion produit d'un acide nucléique analysé selon un procédé CID est reçu. Est également reçu un deuxième spectre de masse d'ion produit de l'acide nucléique analysé selon un procédé de dissociation induite par les radicaux. Les valeurs de pic m/z du premier spectre, les valeurs de pic m/z du deuxième spectre et une valeur m/z d'un ion précurseur de l'acide nucléique sont converties en une charge unique. Une valeur de pic m/z du premier spectre est déterminée laquelle diffère d'une valeur de pic m/z du deuxième spectre par une valeur de masse d'une structure dans l'acide nucléique que le procédé de dissociation induite par les radicaux est connu pour ne pas pouvoir dissocier et que le procédé CID est connu pour pouvoir dissocier. La structure comprend un atome de phosphore et un anneau à cinq chaînons, éventuellement substitué, contenant un oxygène.