WO2024116127 - VENGLUSTAT IN COMBINATION WITH A STRONG OR MODERATE INHIBITOR OF CYP3A4

National phase entry is expected:
Publication Number WO/2024/116127
Publication Date 06.06.2024
International Application No. PCT/IB2023/062098
International Filing Date 30.11.2023
Title **
[English] VENGLUSTAT IN COMBINATION WITH A STRONG OR MODERATE INHIBITOR OF CYP3A4
[French] VENGLUSTAT EN COMBINAISON AVEC UN INHIBITEUR FORT OU MODÉRÉ DE CYP3A4
Applicants **
GENZYME CORPORATION 450 Water Street Cambridge, Massachusetts 02141, US
Inventors
CRAWFORD, Nigel Patrick Somerville c/o Sanofi, Patent Department 450 Water Street Cambridge, Massachusetts 02141, US
LI, Li c/o Sanofi, Patent Department Tower III, Kerry Center 1228 Yan'an Road Jing An District Shanghai 200040, CN
SHARMA, Jyoti c/o Sanofi, Patent Department 450 Water Street Cambridge, Massachusetts 02141, US
ZHANG, Yan-Yan c/o Sanofi, Patent Department Tower III, Kerry Center 1228 Yan'an Road Jing An District Shanghai 200040, CN
Priority Data
63/429,338   01.12.2022   US
Application details
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Entry into National Phase under
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Quotation for National Phase entry

Country StagesTotal
China Filing1886
EPO Filing, Examination9401
Japan Filing589
South Korea Filing575
USA Filing, Examination9910
MasterCard Visa

Total: 22361

The term for entry into the National Phase has expired. This quotation is for informational purposes only

Abstract[English] Provided herein are methods in which patients are administered venglustat in combination with inhibitors of cytochrome CYP3A4. The methods may involve making specific adjustments to the venglustat dosage in order to optimise the clinical response of the patient.[French] L'invention concerne des procédés dans lesquels des patients se voient administrer du venglustat en combinaison avec des inhibiteurs du cytochrome CYP3A4. Les procédés peuvent impliquer la réalisation d'ajustements spécifiques à la dose de venglustat afin d'optimiser la réponse clinique du patient.
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