WO2024116127 - VENGLUSTAT IN COMBINATION WITH A STRONG OR MODERATE INHIBITOR OF CYP3A4

National phase entry is expected:
Publication Number WO/2024/116127
Publication Date 06.06.2024
International Application No. PCT/IB2023/062098
International Filing Date 30.11.2023
Title **
[English] VENGLUSTAT IN COMBINATION WITH A STRONG OR MODERATE INHIBITOR OF CYP3A4
[French] VENGLUSTAT EN COMBINAISON AVEC UN INHIBITEUR FORT OU MODÉRÉ DE CYP3A4
Applicants **
GENZYME CORPORATION
Inventors
CRAWFORD, Nigel Patrick Somerville
LI, Li
SHARMA, Jyoti
ZHANG, Yan-Yan
Priority Data
63/429,338   01.12.2022   US
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting2840
EPO Filing, Examination, Granting16285
Japan Filing, Examination, Granting2657
South Korea Filing, Examination, Granting3027
USA Filing, Examination, Granting11940
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Total: 36,749

The term for entry into the National Phase has expired. This quotation is for informational purposes only

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Abstract[English] Provided herein are methods in which patients are administered venglustat in combination with inhibitors of cytochrome CYP3A4. The methods may involve making specific adjustments to the venglustat dosage in order to optimise the clinical response of the patient.[French] L'invention concerne des procédés dans lesquels des patients se voient administrer du venglustat en combinaison avec des inhibiteurs du cytochrome CYP3A4. Les procédés peuvent impliquer la réalisation d'ajustements spécifiques à la dose de venglustat afin d'optimiser la réponse clinique du patient.