WO2024079665 - NUCLEIC ACID REGULATORY ELEMENTS FOR CONSTITUTIVE GENE EXPRESSION AND METHODS OF USE
National phase entry:
Publication Number
WO/2024/079665
Publication Date
18.04.2024
International Application No.
PCT/IB2023/060252
International Filing Date
11.10.2023
Title **
[English]
NUCLEIC ACID REGULATORY ELEMENTS FOR CONSTITUTIVE GENE EXPRESSION AND METHODS OF USE
[French]
ÉLÉMENTS RÉGULATEURS D'ACIDE NUCLÉIQUE POUR L'EXPRESSION GÉNIQUE CONSTITUTIVE ET MÉTHODES D'UTILISATION
Applicants **
MEIRAGTX UK II LIMITED
Inventors
FORBES, Alexandria
SULLIVAN, Josefa
JIN, Chenjin
MOSSOTTO, Enrico
DURING, Matthew
LIU, Ce Feng
LEE, Dustin
SCHMERLER, Jessica
Priority Data
63/379,138
11.10.2022
US
63/496,554
17.04.2023
US
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
| Number of Priorities | * |
| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
| Pages for Publication | * |
| Number of Pages with Drawings | * |
| Pages of Specification | * |
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| Number of Office Actions | * |
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International Searching Authority |
EPO
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| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
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| Type of Assignment |
The Standard Agent's Assignment
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| Applicant's Legal Status |
Legal Entity
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| * | |
| * | |
| * | |
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| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| Translation |
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* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 9203 | |
| EPO | Filing, Examination, Granting | 91633 | |
| Japan | Filing, Examination, Granting | 4498 | |
| South Korea | Filing, Examination, Granting | 6859 | |
| USA | Filing, Examination, Granting | 32140 |
Total:
144,333
The term for entry into the National Phase has expired. This quotation is for informational purposes only
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Abstract[English]
The application relates to nucleic acid regulatory elements that are able to enhance expression of genes constitutively in a variety of tissues, or in particular tissues including liver, muscle, and the CNS. The application further relates to methods employing these regulatory elements and uses of these elements. Expression cassettes and vectors containing these nucleic acid regulatory elements are also disclosed. These nucleic acid regulatory elements are particularly useful for applications using gene therapy.[French]
La demande concerne des éléments régulateurs d'acide nucléique pouvant améliorer l'expression de gènes de manière constitutive dans une variété de tissus, ou en particulier des tissus comprenant le foie, le muscle et le SNC. La demande concerne en outre des procédés utilisant lesdits éléments régulateurs et des utilisations desdits éléments. Des cassettes d'expression et des vecteurs contenant lesdits éléments régulateurs d'acide nucléique sont également divulgués. Lesdits éléments régulateurs d'acide nucléique sont particulièrement utiles pour des applications utilisant une thérapie génique.