WO2024033896 - OLIGONUCLEOTIDES TARGETING INDOLEAMINE 2,3-DIOXYGENASE AND USES THEREOF

National phase entry is expected:
Publication Number WO/2024/033896
Publication Date 15.02.2024
International Application No. PCT/IB2023/058154
International Filing Date 11.08.2023
Title **
[English] OLIGONUCLEOTIDES TARGETING INDOLEAMINE 2,3-DIOXYGENASE AND USES THEREOF
[French] OLIGONUCLÉOTIDES CIBLANT L'INDOLÉAMINE 2, 3-DIOXYGÉNASE ET LEURS UTILISATIONS
Applicants **
BIORCHESTRA CO., LTD.
Inventors
RYU, Jin-Hyeob
KWON, Mincheol
Priority Data
63/371,343   12.08.2022   US
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting5146
EPO Filing, Examination, Granting101892
Japan Filing, Examination, Granting4944
South Korea Filing, Examination, Granting5533
USA Filing, Examination, Granting41340
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Total: 158,855

The term for entry into the National Phase has expired. This quotation is for informational purposes only

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Abstract[English] The present disclosure relates to small interfering RNAs, which target IDO1 mRNA in a cell, leading to reduced expression of IDO1 protein. Reduction of IDO1 protein expression is beneficial for the treatment of certain medical disorders, e.g., a cancer or a neuronal disease.[French] La présente invention concerne de petits ARN interférents, qui ciblent l'ARNm IDO1 dans une cellule, conduisant à une expression réduite de la protéine IDO1. La réduction de l'expression de la protéine IDO1 est bénéfique pour le traitement de certains troubles médicaux, par exemple, un cancer ou une maladie neuronale.