WO2025003734 - A SYSTEM AND A METHOD FOR POINT-OF-CARE DETECTION OF A BACTERIAL INFECTION

National phase entry is expected:
Publication Number WO/2025/003734
Publication Date 02.01.2025
International Application No. PCT/IB2023/056832
International Filing Date 30.06.2023
Title **
[English] A SYSTEM AND A METHOD FOR POINT-OF-CARE DETECTION OF A BACTERIAL INFECTION
[French] SYSTÈME ET MÉTHODE DE DÉTECTION D'UNE BACTÉRIE À UN POINT D'INTERVENTION
Applicants **
ADEWOLE, Olanisun Olufemi Department of Medicine Obafemi Awolowo University State - Osun Ile Ife, 220103, NG
ADEWOLE, Temitayo Oluwatoyin Department of Family Medicine Obafemi Awolowo University Teaching Hospitals State - Osun Ile Ife, 220103, NG
Inventors
ADEWOLE, Olanisun Olufemi Department of Medicine Obafemi Awolowo University State - Osun Ile Ife, 220103, NG
ADEWOLE, Temitayo Oluwatoyin Department of Family Medicine Obafemi Awolowo University Teaching Hospitals State - Osun Ile Ife, 220103, NG
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Quotation for National Phase entry

Country StagesTotal
China Filing2512
EPO Filing, Examination21945
Japan Filing589
South Korea Filing482
USA Filing, Examination11910
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Total: 37438

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Abstract[English] The present disclosure relates to a system (100) for the detection of bacterial infection in humans. The system comprises an outer surface (101), a pressure-sensitive polyurethane film (103), a microfluidic channel (105), at least one marker (106) and an outlet for removing an excess biofluid (102). The system optionally comprises a lateral flow test strip (200). The system is safe, uses specific antigen-antibody interaction, is accurate, non-invasive allows rapid detection/screening of tuberculosis patients, and is easy to handle without health workers. Further, the present disclosure relates to a method for point-of-care detection of bacterial infection with or without a lateral flow strip (200). The method is specific, non-invasive, rapid, simple, has greater patient compliance and requires less attention from a health care assistant. The system and the method are specifically used to detect Tuberculosis, Anthrax, Tetanus, Pneumonia, Cholera, Diphtheria, Typhoid and Typhus.[French] La présente divulgation concerne un système (100) pour la détection d'une infection bactérienne chez un humain. Le système comprend une surface externe (101), un film de polyuréthane sensible à la pression (103), un canal microfluidique (105), au moins un marqueur (106) et une sortie pour éliminer l'excès de liquide biologique (102). Le système comprend éventuellement une bandelette réactive à écoulement latéral (200). Le système est sûr, utilise une interaction antigène-anticorps spécifique, est précis, non invasif permet une détection ou un dépistage rapide des patients atteints de tuberculose, et est facile à manipuler sans l'aide du personnel médical. En outre, la présente divulgation concerne une méthode de détection d'une infection bactérienne à un point d'intervention, avec ou sans bandelette à écoulement latéral (200). La méthode est spécifique, non invasive, rapide et simple, elle est mieux acceptée par le patient et nécessite moins d'attention de la part du personnel médical. Le système et la méthode sont spécifiquement utilisés pour détecter la tuberculose, la maladie du charbon, le tétanos, la pneumonie, le choléra, la diphtérie, la typhoïde et le typhus.
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