WO2024003668 - HIGH EXPRESSION OF ANIMAL HEME PROTEIN IN PLANTS

National phase entry is expected:
Publication Number WO/2024/003668
Publication Date 04.01.2024
International Application No. PCT/IB2023/056287
International Filing Date 16.06.2023
Title **
[English] HIGH EXPRESSION OF ANIMAL HEME PROTEIN IN PLANTS
[French] EXPRESSION ÉLEVÉE DE PROTÉINE HÉMINIQUE ANIMALE DANS DES PLANTES
Applicants **
MOOLEC SCIENCE LIMITED Innovation Centre, Gallows Hill Warwick CV34 6UW, GB
Inventors
PALADINI, Gaston Jorge Newbery 8655, Country del Lago, lote 79. Rosario, CP2000, AR
SALINAS, Martin La Tradición 3068 Funes, 2132, AR
DHINGRA, Amit 4302 Whitwick Place College Station, Texas 77845, US
HOOGENKAMP, Henk Hoeveveld 24b 6584gg Molenhoek, NL
BENAVIDES, Bruce Williamson 614 S Blaine Street #2 Moscow, Idaho 83843, US
MALVINO, Maria Laura 676 Camino Tierra Santa, apartment 106 Camarillo, California 93010, US
VASUDEVAN, Balaji 120 Weddington Park Ln Apex, North Carolina 27523, US
Priority Data
63/367,299   29.06.2022   US
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Quotation for National Phase entry

Country StagesTotal
China Filing2398
EPO Filing, Examination15903
Japan Filing590
South Korea Filing575
USA Filing, Examination13910
MasterCard Visa

Total: 33376

The term for entry into the National Phase has expired. This quotation is for informational purposes only

Abstract[English] The present disclosure provides methods of producing heme proteins in transgenic plants, plant tissues, or plant cells, as well as describing the expression of these heme proteins in seeds. Also, the present disclosure provides transgenic plants expressing the heme proteins, myoglobin and hemoglobin, by introducing and integrating the recombinant DNA constructs into the host genetic material of the subject plants. The specific combination of regulatory elements disclosed herein allows for high heme protein expression level in seeds.[French] La présente invention concerne des procédés de production de protéines héminiques dans des plantes transgéniques, des tissus végétaux ou des cellules végétales, ainsi que la description de l'expression de ces protéines héminiques dans des graines. La présente invention concerne également des plantes transgéniques exprimant les protéines héminiques, la myoglobine et l'hémoglobine, par introduction et intégration des constructions d'ADN recombinant dans le matériel génétique hôte des plantes concernées. La combinaison spécifique d'éléments régulateurs selon l'invention permet un niveau d'expression de protéine héminique élevée dans des graines.
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