WO2023194837 - MULTI-COMPONENT BUFFER SYSTEM FOR PURIFICATION OF ANTIBODIES

National phase entry:
Publication Number WO/2023/194837
Publication Date 12.10.2023
International Application No. PCT/IB2023/052850
International Filing Date 23.03.2023
Title **
[English] MULTI-COMPONENT BUFFER SYSTEM FOR PURIFICATION OF ANTIBODIES
[French] SYSTÈME TAMPON À COMPOSANTS MULTIPLES POUR LA PURIFICATION D'ANTICORPS
Applicants **
INTAS PHARMACEUTICALS LTD.
Inventors
ADHIKARY, Laxmi
JOGLEKAR, Tushar
VASUDEVAN, Anoop
MODI, Dhrumil
PRAJAPATI, Pragati
PATEL, Niyati
DAKUA, Mukesh
Priority Data
202221020292   04.04.2022   IN
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting1951
EPO Filing, Examination, Granting11561
Japan Filing, Examination, Granting1932
South Korea Filing, Examination, Granting1574
USA Filing, Examination, Granting4740
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Total: 21,758

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Abstract[English] The present invention relates to multi-component buffer system for purification of Antibodies. Specifically, present invention relates cation exchange chromatography process comprising multi-component buffer system and pH based elution for purification of antibodies. The present invention significantly reduces HMW and LMW species including 2H1L species.[French] La présente invention concerne un système tampon à composants multiples pour la purification d'anticorps. Plus particulièrement, la présente invention concerne un procédé de chromatographie par échange de cations comprenant un système tampon à composants multiples et une élution basée sur le pH pour la purification d'anticorps. La présente invention réduit significativement les espèces HMW et LMW comprenant 2 espèces H1L.

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