WO2023194800 - ANTIBODY-DRUG CONJUGATE COMPRISING ANTIBODY AGAINST HUMAN TROP2 AND USE THEREOF

National phase entry:
Publication Number WO/2023/194800
Publication Date 12.10.2023
International Application No. PCT/IB2023/000193
International Filing Date 05.04.2023
Title **
[English] ANTIBODY-DRUG CONJUGATE COMPRISING ANTIBODY AGAINST HUMAN TROP2 AND USE THEREOF
[French] CONJUGUÉ ANTICORPS-MÉDICAMENT COMPRENANT UN ANTICORPS CONTRE LE TROP2 HUMAIN ET SON UTILISATION
Applicants **
LIGACHEM BIOSCIENCES INC.
Inventors
PARK, Chang, Sik
SONG, Ho, Young
KIM, Hye, Jung
CHUNG, Chul-Woong
ALBERTI, Saverio
Priority Data
10-2022-0043049   06.04.2022   KR
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting6246
EPO Filing, Examination, Granting138138
Japan Filing, Examination, Granting4963
South Korea Filing, Examination, Granting6358
USA Filing, Examination, Granting34840
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Total: 190,545

The term for entry into the National Phase has expired. This quotation is for informational purposes only

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Abstract[English] The present disclosure relates to an antibody-drug conjugate (ADC) targeting human TROP2 (tumor-associated calcium signal transducer 2, TACSTD2)) and use thereof, and more particuarly, to: an ADC including an antibody or antigen-binding fragment thereof that binds to human TROP2; and use of ADCs for producing a drug for the treatment and/or treatment of diseases, more particularly, hyperproliferative and/or angiogenic diseases, such as cancer diseases.[French] La présente invention concerne un conjugué anticorps-médicament (ADC) ciblant le TROP2 humain (transducteur de signal calcique associé à une tumeur 2, (TACSTD2)) et son utilisation, et plus particulièrement : un ADC comprenant un anticorps ou un fragment de liaison à l'antigène de celui-ci qui se lie au TROP2 humain; et l'utilisation d'ADC pour produire un médicament pour le traitement et/ou le traitement de maladies, plus particulièrement, de maladies hyperprolifératives et/ou angiogéniques, telles que des maladies cancéreuses.