WO2023067483 - PHARMACEUTICAL COMBINATIONS COMPRISING AN MDM2 INHIBITOR, A BCL2 INHIBITOR AND A HYPOMETHYLATING AGENT AND USES THEREOF FOR THE TREATMENT OF HAEMATOLOGICAL MALIGNANCIES

National phase entry is expected:
Publication Number WO/2023/067483
Publication Date 27.04.2023
International Application No. PCT/IB2022/059973
International Filing Date 18.10.2022
Title **
[English] PHARMACEUTICAL COMBINATIONS COMPRISING AN MDM2 INHIBITOR, A BCL2 INHIBITOR AND A HYPOMETHYLATING AGENT AND USES THEREOF FOR THE TREATMENT OF HAEMATOLOGICAL MALIGNANCIES
[French] COMBINAISONS PHARMACEUTIQUES COMPRENANT UN INHIBITEUR DE MDM2, UN INHIBITEUR DE BCL2 ET UN AGENT D'HYPOMÉTHYLATION ET LEURS UTILISATIONS POUR LE TRAITEMENT DE MALIGNITÉS HÉMATOLOGIQUES
Applicants **
NOVARTIS AG Lichtstrasse 35 4056 Basel, CH
Inventors
FABRE, Claire Novartis Pharma AG Postfach 4002 Basel, CH
HALILOVIC, Ensar Novartis Institutes for BioMedical Research, Inc. 250 Massachusetts Avenue Cambridge, Massachusetts 02139, US
MENSSEN, Hans Dietrich Richard Novartis Pharma AG Postfach 4002 Basel, CH
PATHAK, Dhrubajyoti Novartis Pharma AG Postfach 4002 Basel, CH
Priority Data
63/257,148   19.10.2021   US
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Quotation for National Phase entry

Country StagesTotal
China Filing1765
EPO Filing, Examination10662
Japan Filing596
South Korea Filing575
USA Filing, Examination6310
MasterCard Visa

Total: 19908

The term for entry into the National Phase has expired. This quotation is for informational purposes only

Abstract[English] The invention relates to a pharmaceutical combination comprising an MDM2 inhibitor, a BCL2 inhibitor and a hypomethylating agent. The present invention also relates to methods of treating haematological malignancies involving said combination.[French] L'invention concerne une combinaison pharmaceutique comprenant un inhibiteur de MDM2, un inhibiteur de BCL2 et un agent d'hypométhylation. La présente invention concerne également des méthodes de traitement de malignités hématologiques impliquant ladite combinaison.
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