WO2023037267 - OPTIMIZATION OF DMS SEPARATIONS USING ACOUSTIC EJECTION MASS SPECTROMETRY (AEMS)

National phase entry:
Publication Number WO/2023/037267
Publication Date 16.03.2023
International Application No. PCT/IB2022/058427
International Filing Date 07.09.2022
Title **
[English] OPTIMIZATION OF DMS SEPARATIONS USING ACOUSTIC EJECTION MASS SPECTROMETRY (AEMS)
[French] OPTIMISATION DES SÉPARATIONS DMS PAR SPECTROMÉTRIE DE MASSE À ÉJECTION ACOUSTIQUE (AEMS)
Applicants **
DH TECHNOLOGIES DEVELOPMENT PTE. LTD.
Inventors
SCHNEIDER, Bradley B.
BEDFORD, Leigh
LIU, Chang
Priority Data
63/242,645   10.09.2021   US
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting2851
EPO Filing, Examination, Granting20792
Japan Filing, Examination, Granting2894
South Korea Filing, Examination, Granting3569
USA Filing, Examination, Granting8540
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Total: 38,646

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Abstract[English] Disclosed are methods and systems that provide for the analysis of one or more analytes of interest in an acoustic ejection mass spectrometer (AEMS) system that incorporates an open port interface (OPI) and differentiation mass spectrometry (DMS) that allows for operation of the system in a pseudo-continuous mode to scan and determine optimal DMS settings for the one or more analytes of interest, and for operation of the system in a discontinuous mode to analyze for the presence of the one or more analytes of interest in a sample.[French] La présente invention concerne des procédés et des systèmes qui permettent l'analyse d'un ou plusieurs analytes d'intérêt dans un système de spectromètre de masse à éjection acoustique (AEMS) qui intègre une interface à port ouvert (OPI) et une spectrométrie de masse par différenciation (DMS) qui permet le fonctionnement du système en mode pseudo-continu pour balayer et déterminer les paramètres de DMS optimaux pour le ou les analytes d'intérêt, et le fonctionnement du système en mode discontinu pour analyser la présence du ou des analytes d'intérêt dans un échantillon.